Results 31 to 40 of about 491,786 (306)

Contrasting actions of ginsenosides Rb1 and Rg1 on glucose tolerance in rats

Chinese Journal of Physiology, 2019
Ginsenoside profile of Panax ginseng is changing with season and cultivated soil. Yet, dose-response relationship of main ginsenosides on metabolic measures has not been documented in vivo.
Rungchai Chaunchaiyakul, Naruemon Leelayuwat, Jin-Fu Wu, Chih-Yang Huang, Chia-Hua Kuo   +4 more
doaj   +1 more source

The Oral Glucose Tolerance Test: 100 Years Later

Diabetes, Metabolic Syndrome and Obesity, 2020
Ram Jagannathan,1 João Sérgio Neves,2,3 Brenda Dorcely,4 Stephanie T Chung,5 Kosuke Tamura,6 Mary Rhee,7 Michael Bergman8 1Division of Hospital Medicine, Emory University School of Medicine, Atlanta, GA, USA; 2Department of Surgery and ...
Jagannathan R, Neves JS, Dorcely B, Chung ST, Tamura K, Rhee M, Bergman M   +6 more
doaj  

Role of positive glucose challenge test only versus oral glucose tolerance test in pregnancy outcome: a comparative study

Journal of Pathology of Nepal, 2019
Background: Gestational diabetes mellitus is defined as any degree of glucose intolerance which is first recognized during pregnancy and is associated with a number of adverse perinatal outcomes, such as neonatal hypoglycemia, macrosomia with an ...
Neha Homagai, Nirajan Mainali, Sikha Rijal   +2 more
doaj   +1 more source

To Evaluate the Effect of Edrophonium on Blood Glucose Levels in Euglycemic Albino Rats Through OGTT [PDF]

Journal of Clinical and Diagnostic Research, 2015
Objective: To evaluate the effect of Edrophonium on blood glucose levels in euglycemic albino rats through OGTT. Materials and Methods: Twelve Swiss albino rats weighing around 150-200 gms of either sex were randomly selected from the central animal ...
Siddamma Amoghimath, Suresha R N, Jayanthi M K, Shruthi S L, Vaibhavi PS, Satish A M, Pushpa V H, Kalabharathi H L   +7 more
doaj   +1 more source

Antihyperglycemic effects of Lysiphyllum strychnifolium leaf extract in vitro and in vivo

Pharmaceutical Biology, 2023
Context Lysiphyllum strychnifolium (Craib) A. Schmitz (LS) (Fabaceae) has traditionally been used to treat diabetes mellitus.Objective This study demonstrates the antidiabetic and antioxidant effects of aqueous extract of LS leaves in vivo and in vitro ...
Arman Syah Goli, Vilasinee Hirunpanich Sato, Hitoshi Sato, Savita Chewchinda, Jiraporn Leanpolchareanchai, Jannarin Nontakham, Jantana Yahuafai, Thavaree Thilavech, Pongsatorn Meesawatsom, Metawee Maitree   +9 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens, Bernstein, Berthoud, Berthoud, Bloom, Bloom, Daniel, De Groot, De Jong, E.C. Lotter, F. Kuipers, Frohman, Frohman, G. Flik, Henquin, Inoue, Iversen, Iversen, Kaneto, Kaneto, Kaneto, Kaneto, Karam, Matsushita, McCaleb, Moltz, P.G.M. Luiten, Robertson, Shimazu, Shimazu, Shimazu, Steffens, Steffens, Strubbe, Strubbe, Strubbe   +35 more
core   +8 more sources

Prolonged plasma glucose elevation on oral glucose tolerance test in young healthy Japanese individuals

Endocrinology, Diabetes & Metabolism, 2020
Aims This study aims to assess insulin secretion and resistance through oral glucose tolerance test (OGTT) among young Japanese individuals. Subjects and methods We enrolled 595 young healthy Japanese individuals aged 22‐29 years. They underwent an OGTT,
Hirotaka Ishigaki, Akihiro Yoshida, Osamu Araki, Takao Kimura, Katsuhiko Tsunekawa, Yoshifumi Shoho, Makoto Nara, Tomoyuki Aoki, Takayuki Ogiwara, Masami Murakami   +9 more
doaj   +1 more source

Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. [PDF]

PLoS ONE, 2009
BACKGROUND: The prevalence of overweight is increasing globally and has become a serious health problem. Low-grade chronic inflammation in overweight subjects is thought to play an important role in disease development.
Suzan Wopereis, Carina M Rubingh, Marjan J van Erk, Elwin R Verheij, Trinette van Vliet, Nicole H P Cnubben, Age K Smilde, Jan van der Greef, Ben van Ommen, Henk F J Hendriks   +9 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source