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Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

Clinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund, Annette Haerdtlein, Wolfgang Fehrmann, Clara Weglage, Tobias Dreischulte, Ulrich Jaehde   +5 more
wiley   +1 more source

Vericiguat improves cardiac remodelling and function in rats with doxorubicin‐induced cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Purpose Vericiguat, a soluble guanylate cyclase (sGC) stimulator, has been demonstrated effective in improving prognosis of patients with heart failure with reduced ejection fraction. However, there are limited data concerning the effect of vericiguat in patients with doxorubicin (DOX)‐induced cardiomyopathy (DIC).
Wen Chen, Ying Wu, Wei Li, Meiyan Song, Kaizu Xu, Meifang Wu, Liming Lin   +6 more
wiley   +1 more source

Clinical Accuracy of a Glucose Oxidase-Based Blood Glucose Test-Strip Across Extremes of Oxygen Partial Pressure. [PDF]

J Diabetes Sci Technol
Setford S, Phillips S, Cameron H, Grady M.   +3 more
europepmc   +1 more source

Biomarkers in heart failure: Traditional and emerging indicators for prognosis

ESC Heart Failure, EarlyView.
Arnold Péter Ráduly, László Nagy, Beáta Bódi, Zoltán Papp, Attila Borbély   +4 more
wiley   +1 more source

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Glucose oxidase: Applications, sources, and recombinant production

Biotechnology and applied biochemistry, 2021
Glucose oxidase is a subset of oxidoreductase enzymes that catalyzes the transfer of electrons from an oxidant to a reductant. Glucose oxidases use oxygen as an external electron acceptor that releases hydrogen peroxide (H2O2).
S. H. Khatami, Omid Vakili, Nahid Ahmadi, Elahe Soltani Fard, P. Mousavi, B. Khalvati, A. Maleksabet, A. Savardashtaki, M. Taheri‐Anganeh, A. Movahedpour   +9 more
semanticscholar   +1 more source

Co–Ferrocene MOF/Glucose Oxidase as Cascade Nanozyme for Effective Tumor Therapy

Advanced Functional Materials, 2020
Chemodynamic therapy (CDT), enabling selective therapeutic effects and low side effect, attracts increasing attention in recent years. However, limited intracellular content of H2O2 and acid at the tumor site restrains the lasting Fenton reaction and ...
Chao Fang, Z. Deng, Guodong Cao, Q. Chu, Yulian Wu, Xiang Li, Xinsheng Peng, G. Han   +7 more
semanticscholar   +1 more source

Glucose oxidase — An overview

Biotechnology Advances, 2009
Glucose oxidase (beta-D-glucose:oxygen 1-oxidoreductase; EC 1.1.2.3.4) catalyzes the oxidation of beta-D-glucose to gluconic acid, by utilizing molecular oxygen as an electron acceptor with simultaneous production of hydrogen peroxide. Microbial glucose oxidase is currently receiving much attention due to its wide applications in chemical ...
Rekha S. Singhal, Mahesh V. Bule, Sandip B. Bankar, Laxmi Ananthanarayan   +3 more
openaire   +3 more sources

Specificity of glucose oxidase

Archives of Biochemistry and Biophysics, 1960
Abstract The specificity of glucose oxidase for catalyzing the oxidation of β- d -glucose in contrast to α- d -glucose, other hexoses, and pentoses was investigated. The enzyme appears to catalyze the oxidation of the beta form only, and the mutarotation of the alpha form is rate limiting.
Ernest C. Adams, Alfred H. Free, Raymond L. Mast   +2 more
openaire   +3 more sources

Glucose Oxidase‐Related Cancer Therapies

, 2020
Glucose oxidase (GOx), which catalyzes the conversion of glucose into gluconic acid and hydrogen peroxide (H2O2) in the presence of oxygen (O2), has aroused growing interest for cancer therapy.
Chunhui Wang, Jingxian Yang, Chunyan Dong, Shuo Shi   +3 more
semanticscholar   +1 more source

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

Chemical Society Reviews, 2018
Glucose oxidase (GOx) is an endogenous oxido-reductase that is widely distributed in living organisms. Over recent years, GOx has attracted increasing interest in the biomedical field due to its inherent biocompatibility, non-toxicity, and unique ...
Chao Qi, Lian-hua Fu, Jing Lin
exaly   +2 more sources