Results 131 to 140 of about 184,524 (356)

Regulation of the microglial NADPH oxidase by neurotransmitters: implications for microglial – neuronal interactions

open access: yes, 2012
Neurotransmitter dysregulation and reactive oxygen species (ROS) are a hallmark of neurodegenerative disease. Microglia, the immune cells of the CNS, express three NADPH oxidase isoforms (Nox1, Nox2 and Nox4), which produce superoxide that is used as an ...
Mead, E.L.
core  

Expression and overproduction of glucose oxidase in Aspergillus niger

open access: yes, 1992
This report describes the expression of cloned glucose oxidase gene (god) in glucose-oxidase-deficient mutants (God−) of Aspergillus niger NRRL-3, the use of this gene for the elevation of glucose oxidase (GOD) productivity in the parental strain, and ...
Alaeddinoglu, N Gürdal   +1 more
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

NATURE OF POLYETHYLENEIMINE-GLUCOSE OXIDASE INTERACTIONS

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2016
The nature of interactions between Polyethylenimine and glucose oxidase 3QVR enzyme was studied by docking and Molecular dynamics procedures. The docking procedure evidenced two active sites, one located inside the enzyme body and the second at the ...
Beata SZEFLER   +2 more
doaj  

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao   +11 more
wiley   +1 more source

Studies on glucose oxidase

open access: yes, 1978
학위논문(석사) - 한국과학기술원 : 생물공학과, 1978.2, [ vii, 74 p. ]Glucose oxidase의 생산과 정제에 관한 연구가 시도되었다. 여러개의 곰팡이로 부터 glucose oxidase 생산에 관해 실험한 결과, Penicillium sp.가 가장 많은 glucose oxidase를 배양액 중에 배출해 내었다. 이 미생물은 아직 동정되지 않았다.
고중환, Ko, Jung-Hwan
core  

Polymer‐Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring

open access: yesAdvanced Science, EarlyView.
A monolithic integrated photonic chip simultaneously measures blood glucose, pressure, temperature, ECG, and sweat glucose. Combining multiple Bragg grating sensors, Mach–Zehnder modulators, and an on–‐chip demodulation unit, this compact chip (1 cm × 0.5 cm) offers robust multiparameter detection.
Xiaolin Li   +11 more
wiley   +1 more source

β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase

open access: yes, 2004
β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y.   +2 more
core  

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