Results 101 to 110 of about 84,281 (289)
Nature Communications, 2017 Cancer cell survival under metabolic stress is a critical step for metastasis. Here, the authors show that under glucose deprivation, Snail, a key regulator of the metastatic process, promotes survival by diverting glucose to the pentose phosphate ...
Nam Hee Kim +20 more
doaj +1 more source
Towards a comprehensive modeling framework for studying glucose repression in yeast [PDF]
, 2022 The yeast Saccharomyces cerevisiae is an important model organism for human health and for industry applications as a cell factory. For both purposes, it has been an important organism for studying glucose repression.
6sterberg, Linnea
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Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Advanced Science, EarlyView.Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Site of glucose repression of heme biosynthesis [PDF]
FEBS Letters, 1974 Poulson, Rozanne, Polglase, W.James
openaire +2 more sources
Molecular genetic analysis of glucose repression in Drosophila.
, 1992 The research described in this thesis focuses on glucose repression of gene expression in a higher eukaryotic organism, the fruit fly Drosophila melanogaster. The results show that DNA sequences which are located upstream of the transcribed region of the
Magoulas, Charalambos.
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Advanced Science, EarlyView.A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa +8 more
wiley +1 more source
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
eLifeMany cells in high glucose repress mitochondrial respiration, as observed in the Crabtree and Warburg effects. Our understanding of biochemical constraints for mitochondrial activation is limited.
Vineeth Vengayil +4 more
doaj +1 more source
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source