Results 131 to 140 of about 8,218,774 (258)

Relationship of circulating fetuin-A with the insulinogenic index, adjusted for age, sex and insulin sensitivity estimated from the oral glucose tolerance test, in subjects with normal glucose tolerance (N = 267; A) and impaired glucose tolerance (N = 91, B).

, 2014
Relationship of circulating fetuin-A with the insulinogenic index, adjusted for age, sex and insulin sensitivity estimated from the oral glucose tolerance test, in subjects with normal glucose tolerance (N = 267; A) and impaired glucose tolerance (N = 91,
Qi Sun (127), Matthias B. Schulze (125913), Frank B. Hu (127167), Charlotte Jeppesen (413704), Susanne Ullrich (193452), Hans-Georg Joost (106886), Fritz Schick (176974), Norbert Stefan (83540), Jürgen Machann (176966), Andreas Fritsche (36362), Felicia Gerst (538634), Heiner Boeing (23585), Hans-Ulrich Häring (36363)   +12 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

DHEA treatment impairs glucose tolerance in C57Bl6 female mice.

, 2013
A. Glucose tolerance test of BALB/cByJ females, treated and untreated. n = 7–9. B. Glucose tolerance test of C57Bl6 females, treated and untreated. n = 10. C. Fasting glucose levels of BALB/cByJ and C57Bl6 females.
Abigail R. Dowling (301031), Laura B. Nedorezov (487435), Joseph S. Marino (301029), Xiaoliang Qiu (487436), Jennifer W. Hill (301036)   +4 more
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

The Effect of L-Carnitine Treatment on Lactic Acid Levels in Normal Subjects and Patients with IGT

Endocrinology Research and Practice, 2005
Principles: Previous studies have demonstrated that L-carnitine has important effects on the mitochondrial beta oxidation of long-chain fatty acids and glucose metabolism. In the present study, effects of the L-carnitine on lactic acid levels and glucose
Mustafa Sait Gönen, Gürcan Kısakol, Kağan Güngör, Oğuz Dikbaş, Ahmet Kaya   +4 more
doaj   +2 more sources

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Maternal hyperglycemia and the oral glucose tolerance test

Taiwanese Journal of Obstetrics & Gynecology, 2015
Horng-Jyh Tsai
doaj   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source