Results 41 to 50 of about 199,721 (141)

Cardiovascular consequences of diabetes mellitus [PDF]

, 1999
Diabetes mellitus comprises a clinically and genetically heterogeneous group of disorders that have one common feature: abnormally high levels of glucose in the blood.
Baan, C.A. (Caroline)
core   +2 more sources

Impaired Glucose Metabolism in Liver Cirrhosis [PDF]

, 2013
Background: Approximately 30% of patients who suffer cirrhosis maybe diabetic, called hepatogenous diabetes (HD). Insulin resistance seems to be the pathophysiologic basis for HD.
Ndraha, S. (Suzanna), Santoso, M. (Mardi), Sunardi, I. D. (Ivan), Tendean, M. (Marshel), Wician, F. (Fendra)   +4 more
core   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Impact of Intermittent Hypoxia on the Glycemic Response to an Oral Glucose Tolerance Test [PDF]

, 2022
Hypoxia triggers glucose uptake independently from the action of insulin. PURPOSE: To determine the acute effect of intermittent hypoxia, defined as alternating short bouts of breathing hypoxic and room air, on plasma glucose levels during an oral ...
Lalande, Sophie, Massoudian, Sahar D, Wojan, Frank, Zhao, Jiahui   +3 more
core   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Predictive factors of developing diabetes mellitus in women with gestational diabetes. [PDF]

, 2002
BACKGROUND: To investigate which factors during gestational diabetes pregnancies correlate with the risk of developing impaired glucose tolerance or diabetes 1 year postpartum and to compare this risk in women with gestational diabetes and women with a ...
Aberg A, AndersE. B. Åberg, AndersH. Frid, Catalano PM, Cnattingius S, Coustan DR, Coustan DR, Damm P, Damm P, Dornhorst A, Eriksson K-F, EvaK. Jönsson, Fuchtenbusch M, Hakansson A, Henry OA, Inger Eskilsson, Kjos SL, Lam KSL, Lind T, Marsal K, Mestman JH, Metzger BE, Mona Landin-Olsson, O'Sullivan JB, O'Sullivan JB, O'Sullivan JB, O'Sullivan JB, Persson B, Persson P-H, Peters RK, Turner RC   +30 more
core   +2 more sources

UDP‐glucose dehydrogenase variants cause dystroglycanopathy

Annals of Clinical and Translational Neurology, EarlyView.
Abstract UDP‐glucose dehydrogenase (UGDH) variants have been associated with hypotonia, developmental delay, and epilepsy. We report the first pathologic evidence of dystroglycanopathy in siblings with UGDH variants. Both presented around 6 months with developmental delay and elevated creatinine kinase.
Anna M. Reelfs, Carrie M. Stephan, Theresa M. Czech, Mary O. Cox, Soumya Joseph, Benjamin W. Darbro, Steven A. Moore, Kevin P. Campbell, Katherine D. Mathews   +8 more
wiley   +1 more source

A1C Testing in the Diagnosis of Diabetes Mellitus [PDF]

, 2006
A1C testing is highly specific compared with a two-hour oral glucose tolerance test (OGTT) or a fasting plasma glucose test. However, because A1C testing is not sensitive enough to rule out diabetes if levels are normal, the test should not be used for ...
Lee, Tae Joon, Safranek, Sarah
core  

Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance [PDF]

, 2016
Aim: To investigate glucose and insulin metabolism in participants with ataxia telangiectasia in the absence of a diagnosis of diabetes. Methods: A standard oral glucose tolerance test was performed in participants with ataxia telangiectasia (n ...
Cremona, Halaby, Madiraju, Matsuda, Matuoka, Miles, Morio, Otten, Rena, Schalch, Schiekofer, Schneider, Takagi, The GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group & The Wellcome Trust Case Control Consortium 2, Yang   +14 more
core   +3 more sources

The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Determine the association between diabetes and metabolic syndrome (MetS) burden (number of MetS criteria fulfilled) and pain, neuropathy severity, and fiber type involvement in individuals with established polyneuropathy. Methods The Peripheral Neuropathy Research Registry was queried for individuals with type 1 and type 2 diabetes ...
Long Davalos, Brian C. Callaghan, Lavanya Muthukumar, Simone Thomas, Evan L. Reynolds, A. Gordon Smith, J. Robinson Singleton, Ahmet Höke, Senda Ajroud‐Driss, Mazen M. Dimachkie, Stefanie Geisler, David M. Simpson, PNRR Study Group, Amro M. Stino   +13 more
wiley   +1 more source