Results 51 to 60 of about 435,255 (308)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The Oral Glucose Tolerance Test: 100 Years Later

Diabetes, Metabolic Syndrome and Obesity, 2020
Ram Jagannathan,1 João Sérgio Neves,2,3 Brenda Dorcely,4 Stephanie T Chung,5 Kosuke Tamura,6 Mary Rhee,7 Michael Bergman8 1Division of Hospital Medicine, Emory University School of Medicine, Atlanta, GA, USA; 2Department of Surgery and ...
Jagannathan R, Neves JS, Dorcely B, Chung ST, Tamura K, Rhee M, Bergman M   +6 more
doaj  

Prediabetes and working memory in older adults

Brain and Neuroscience Advances, 2020
Insulin sensitivity, pancreatic β-cell function, fasting glucose, and 2-h post-load glucose were related to cognition in cognitively healthy nondiabetic older adults.
Gilda E. Ennis, Ursula Saelzler, Guillermo E. Umpierrez, Scott D. Moffat   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The glycemic elemental profile of trichosanthes dioica: a LIBS-based study [PDF]

, 2010
The scientific evaluation of the antidiabetic efficacy of aqueous extract of Trichosanthes dioica fruits on streptozotocin-induced diabetic rats is being presented. The graded doses of the extract, viz., 500, 750, 1,000, and 1,250 mg/kg body weight (bw),
Bicanic, D.D., Chatterji, S., Rai, N.K., Rai, P.K., Watal, G.   +4 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Effects of a Mindfulness-Based Intervention on Distress, Weight Gain, and Glucose Control for Pregnant Low-Income Women: A Quasi-Experimental Trial Using the ORBIT Model. [PDF]

, 2019
BackgroundStress can lead to excessive weight gain. Mindfulness-based stress reduction that incorporates mindful eating shows promise for reducing stress, overeating, and improving glucose control. No interventions have tested mindfulness training with a
Adler, N, Bush, N, Coleman-Phox, K, Dallman, M, Epel, E, Hecht, FM, Kristeller, JL, Laraia, B, Leung, C, Lustig, RH, Mellin, L, Stotland, N, Thomas, M, Vieten, C   +13 more
core  

Sleep Disturbances and Glucose Metabolism in Older Adults: The Cardiovascular Health Study. [PDF]

, 2015
ObjectiveWe examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 ...
Biggs, Mary Lou, Carnethon, Mercedes, Djoussé, Luc, Janszky, Imre, Kaplan, Robert C, Mukamal, Kenneth J, Patel, Sanjay R, Redline, Susan, Robbins, John A, Siscovick, David S, Strand, Linn Beate   +10 more
core   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Comparison between 100-g glucose tolerance test and two other screening tests for gestational diabetes: combined fasting glucose with risk factors and 50-g glucose tolerance test

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Lack of consensus about which screening tests to use for gestational diabetes mellitus (GDM) and difficulties in performing the gold-standard diagnostic test, the 100-g glucose tolerance test (100-g GTT), justify comparison with ...
Wilson Ayach, Roberto Antonio Araújo Costa, Iracema de Mattos Paranhos Calderon, Marilza Vieira Cunha Rudge   +3 more
doaj   +1 more source