Results 51 to 60 of about 246,840 (307)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Guideline for screening and diagnosing gestational diabetes mellitus [PDF]

open access: yes, 2015
Gestational diabetes mellitus (GDM) is on the rise, especially with the increase in obesity in childbearing women as well as the rising prevalence of diabetes mellitus type 2.
Craus, Johann   +2 more
core  

The Oral Glucose Tolerance Test: 100 Years Later

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Ram Jagannathan,1 João Sérgio Neves,2,3 Brenda Dorcely,4 Stephanie T Chung,5 Kosuke Tamura,6 Mary Rhee,7 Michael Bergman8 1Division of Hospital Medicine, Emory University School of Medicine, Atlanta, GA, USA; 2Department of Surgery and ...
Jagannathan R   +6 more
doaj  

The effect of glucose tolerance test on fetoplacental circulation [PDF]

open access: yesAl-Azhar International Medical Journal
Background: The prevalence of gestational diabetes mellitus (GDM), a common pregnancy complication, differs with race and ethnicity. Aim: Studying the effects of a 50-gram oral glucose tolerance test (OGTT) on fetal and placental circulation in pregnant
Aya Hussien   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at? [PDF]

open access: yes, 2009
Zhao X, Peter A, Fritsche J, Elcnerova M, Fritsche A, Haring HU, Schleicher ED, Xu G, Lehmann R. Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?
Fritsche, Jens   +9 more
core   +1 more source

Maternal hyperglycemia and the 100-g oral glucose tolerance test

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2015
Objectives: To compare the characteristics of pregnant women with hyperglycemia according to the severity of glucose intolerance using the 100-g oral glucose tolerance test (OGTT) and to demonstrate the need to manage the condition of women with mild ...
Tae-Chul Park   +3 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Impact of glucose excursion and mean glucose concentration in oral glucose-tolerance test on oxidative stress among Japanese Americans [PDF]

open access: yes, 2013
Shuhei Nakanishi, Masayasu Yoneda, Shusaku Maeda Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan Aim: To evaluate the impact of glucose excursion (GE) and mean ...
Maeda S, Yoneda M, Nakanishi S
core  

Abnormal glucose tolerance and lung function in children with cystic fibrosis. Comparing oral glucose tolerance test and continuous glucose monitoring [PDF]

open access: yes, 2021
BACKGROUND: Cystic fibrosis (CF) related diabetes (CFRD) is a common complication of CF. CFRD is associated with declining lung function even before its onset.
Hansen, C R   +3 more
core   +1 more source

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