Results 61 to 70 of about 435,255 (308)

Improved insulin sensitivity following a short-term whole body vibration intervention [PDF]

, 2017
Background and Objective: Despite being recommended for reducing the risk of type 2 diabetes (T2D) the majority of the population do not partake in the advised amount of regular exercise.
Babraj, John, Hawkey, Adam
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk [PDF]

, 2017
We aimed to examine heterogeneity in glucose response curves during an oral glucose tolerance test with multiple measurements and to compare cardiometabolic risk profiles between identified glucose response curve groups.
Alssema, M, Astrup, A, Dekker, JM, Eiberg, H, Færch, K, Gjesing, AP, Hansen, T, Hulman, A, Jonsson, A, Kirwan, JP, Koopman, AD, Pedersen, O, Rutters, F, Simmons, RK, Solomon, TP, Sørensen, TI, Tabák, AG, Vistisen, D, Witte, DR   +18 more
core  

Host-microbiome interactionsin human type 2 diabetes following prebiotic fibre (galactooligosaccharide) intake [PDF]

, 2016
Aberrant microbiota composition and function have been linked to several pathologies, including type 2 diabetes. In animal models, prebiotics induce favourable changes in the intestinal microbiota, intestinal permeability (IP) and endotoxaemia, which are
Camilla Pedersen, Edith Gallagher, Etana Jaiyeola, Felicity Horton, Friedewald, Glenn R. Gibson, Huihai Wu, John Wright, Lambeth, M. Denise Robertson, Onyinye Diribe, Patrice D. Cani, Paul Hinton, Richard J. Ellis, Roberto La Ragione, Thibaut Duparc, Umer Z. Ijaz   +16 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Association of glucose tolerance status with pancreatic β‐ and α‐cell mass in community‐based autopsy samples of Japanese individuals: The Hisayama Study

Journal of Diabetes Investigation, 2020
Aims/Introduction Changes in histologically quantified β‐ and α‐cell mass during the development of glucose intolerance have not been fully elucidated. The aim of the present study was to explore differences in β‐ and α‐cell mass according to the glucose
Jun Inaishi, Yoshifumi Saisho, Yoichiro Hirakawa, Daigo Yoshida, Jun Hata, Naoko Mukai, Yuusuke Watanabe, Yoshinao Oda, Hiroshi Itoh, Toshiharu Ninomiya   +9 more
doaj   +1 more source

Cardiovascular consequences of diabetes mellitus [PDF]

, 1999
Diabetes mellitus comprises a clinically and genetically heterogeneous group of disorders that have one common feature: abnormally high levels of glucose in the blood.
Baan, C.A. (Caroline)
core   +2 more sources

THE INTRAVENOUS GLUCOSE TOLERANCE TEST [PDF]

Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1956
1. Two indices of glucose tolerance, the “total index” and the “increment index”, derived from an intravenous glucose tolerance test have been defined, and determined in, 20 normal and 15 diabetic subjects.2. The “total index” is based on the assumption that the rate of fall of blood glucose remains consistently proportional to the total blood glucose ...
openaire   +2 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Clinical implications of combined glucose intolerance in treatment-naïve hypertensive patients

Clinical and Experimental Hypertension, 2018
Background: This study is the first study to evaluate clinical significance of combined glucose intolerance (CGI) in treatment-naïve hypertensive patients. Methods: We compared the results of demographic, anthropometric, clinical, laboratory examinations,
Beom-June Kwon, Dae-Won Kim, Mahn-Won Park, Sung-Ho Her, Ha Wook Park, Kiyuk Chang, Wook-Sung Chung, Ki-Bae Seung, Tai-Ho Rho   +8 more
doaj   +1 more source