In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Evaluation of glucose tolerance test and surrogate indexes of insulin sensitivity to detect insulin resistance syndrome in transition dairy cows [PDF]
Healthy multiparous Holstein-Fresian cows (n=101, parity ≥ 2) from 3 large-scale dairy herds in Italy were subjected to an intravenous glucose tolerance test (GTT) 14-1 d before (Week -1) and 3-9 d after calving (Week +1).
Riuzzi, Sara
core
Glucoregulatory and order effects on verbal episodic memory in healthy adolescents after oral glucose administration [PDF]
The ingestion of oral glucose has been observed to facilitate memory performance in both elderly individuals and in young adults. However, fewer studies have investigated the effect of glucose on memory in children or adolescents.
Jonathan K. Foster +4 more
core +1 more source
High prevalence of undiagnosed impaired glucose tolerance in patients with rheumatoid arthritis
Objectives: Although the risk of diabetes mellitus has been recognised in rheumatoid arthritis, undiagnosed dysglycaemia remained under-reported. The study aimed to determine the prevalence and associated factors of dysglycaemia among patients with ...
Nur ‘Aini Eddy Warman +6 more
doaj +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
In vivo laboratory practicals in research-led teaching: An example using glucose tolerance tests in lean and obese mice [PDF]
The use of animal models is an essential part of medical research and drug development. The essential skills required to be able to do such research includes experimental design, statistical analysis and the actual handling and treating of the animals ...
Ian M. Kinchin +10 more
core +1 more source
CONTEXT AND OBJECTIVE: Lack of consensus about which screening tests to use for gestational diabetes mellitus (GDM) and difficulties in performing the gold-standard diagnostic test, the 100-g glucose tolerance test (100-g GTT), justify comparison with ...
Wilson Ayach +3 more
doaj +1 more source
EFFECT OF INDUCED ACUTE PANCREATITIS AND INDUCED EXPERIMENTAL DIABETS ON GLUCOSE TOLERANCE IN CATTLE AND BUFFALOES [PDF]
Acute pancereatitis and diabetes were experimentally induced in cattle and buffaloes to study the effect of the diseases on glucose tolerance. The (K) value (glucose disappear ance coefficient, measured in percentage,' decrease of glucose/min) was ...
M.S. HASSAN +4 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Blood glucose levels in oral glucose tolerance test (A) and insulin tolerance test (B). [PDF]
Values are expressed as mean ± SEM of 5 mice for each group. No significant differences were seen in blood glucose levels between G and W groups at any time point in the oral glucose tolerance test and the insulin tolerance test.
Mototsugu Nagao (508631) +4 more
core +1 more source

