Results 141 to 150 of about 99,255 (339)

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

open access: yesMolecular Nutrition &Food Research, EarlyView.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García   +4 more
wiley   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

GLUCOSIDE FORMATION IN THE COMMONER MONOSES

open access: hybrid, 1932
P.A. Levene   +2 more
openalex   +1 more source

Development of a Wine By‐Product‐Based Beverage and Study of Its Potential to Postprandial Glycemia Regulation in Healthy Individuals: A Proof of Concept Study

open access: yesMolecular Nutrition &Food Research, EarlyView.
The postprandial glycemia of healthy adults is not downregulated by the coadministration of a sugar solution and a wine by‐product enriched beverage due to the high variability in the response. Blood phenolic compounds of responders’ volunteers are not associated with the reduction effect of postprandial hyperglycemia.
María‐José Motilva   +2 more
wiley   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

open access: yesNeuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng   +9 more
wiley   +1 more source

A New Sarsasapogenin Glucoside from Narthecium ossifragum (L.) Huds. [PDF]

open access: bronze, 1954
Arnulv Stabursvik   +3 more
openalex   +1 more source

Trikafta Rescues F508del‐CFTR by Tightening Specific Phosphorylation‐Dependent Interdomain Interactions

open access: yesNatural Sciences, EarlyView.
The most common cystic fibrosis mutation, F508del, destabilizes the first of two nucleotide‐binding domains (NBD1 and NBD2) and compromises Mg/ATP‐dependent gating at the interface between two transmembrane domains (TMD1 and TMD2) in the human cystic fibrosis transmembrane conductance regulator (CFTR).
Guangyu Wang
wiley   +1 more source

Home - About - Disclaimer - Privacy