Results 21 to 30 of about 15,247 (253)

AKR1A1 Variant Associated With Schizophrenia Causes Exon Skipping, Leading to Loss of Enzymatic Activity

Frontiers in Genetics, 2021
Schizophrenia is a heterogeneous psychiatric disorder characterized by positive symptoms such as hallucinations and delusions, negative symptoms such as anhedonia and flat affect, and cognitive impairment.
Kyoka Iino, Kazuya Toriumi, Riko Agarie, Mitsuhiro Miyashita, Mitsuhiro Miyashita, Mitsuhiro Miyashita, Kazuhiro Suzuki, Kazuhiro Suzuki, Yasue Horiuchi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Itaru Kushima, Itaru Kushima, Shinsuke Koike, Tempei Ikegame, Seiichiro Jinde, Eiichiro Nagata, Shinsuke Washizuka, Toshio Miyata, Shunya Takizawa, Ryota Hashimoto, Kiyoto Kasai, Kiyoto Kasai, Norio Ozaki, Masanari Itokawa, Masanari Itokawa, Makoto Arai   +28 more
doaj   +1 more source

Functional metabolomics discover pentose and glucuronate interconversion pathways as promising targets for Yang Huang syndrome treatment with Yinchenhao Tang

RSC Advances, 2018
Xi-jun Wang
exaly   +3 more sources

Integrated 16S rDNA sequencing and metabolomics to explore the intestinal changes in children and rats with dental fluorosis

Ecotoxicology and Environmental Safety, 2023
Dental fluorosis (DF) is a widely prevalent disease caused by excessive fluoride with limited awareness of its underlying pathogenesis. Here, a pilot population study was conducted to explore the pathogenesis of DF from the perspective of intestinal ...
Guoyu Zhou, Qingyuan Li, Xiangbo Hou, Huiying Wu, Xiaoli Fu, Guoqing Wang, Jun Ma, Xuemin Cheng, Yang Yang, Ruiqin Chen, Zhiyuan Li, Fangfang Yu, Jingyuan Zhu, Yue Ba   +13 more
doaj   +1 more source

Differential and shared effects of eicosapentaenoic acid and docosahexaenoic acid on serum metabolome in subjects with chronic inflammation

Scientific Reports, 2021
The omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) affect cell function and metabolism, but the differential effects of EPA and DHA are not known. In a randomized, controlled, double-blind, crossover study, we assessed the
Wan-Chi Chang, Jisun So, Stefania Lamon-Fava   +2 more
doaj   +1 more source

Rapid Stimulation of Free Glucuronate Formation by Non-glucuronidable Xenobiotics in Isolated Rat Hepatocytes [PDF]

Journal of Biological Chemistry, 2003
Carole L Linster, Emile Van Schaftingen
exaly   +2 more sources

Screening and Regulation Mechanism of Key Transcription Factors of Penicillium expansum Infecting Postharvest Pears by ATAC-Seq Analysis

Foods, 2022
Transcription factors play a key role in Penicillium expansum infection process. Although the crucial characteristics of some transcription factors of pathogenic fungi have been found, many transcription factors involved in P.
Lina Zhao, Yuling Shu, Sihao Quan, Solairaj Dhanasekaran, Xiaoyun Zhang, Hongyin Zhang   +5 more
doaj   +1 more source

Molecular theory of solvation: Methodology summary and illustrations [PDF]

, 2015
Integral equation theory of molecular liquids based on statistical mechanics is quite promising as an essential part of multiscale methodology for chemical and biomolecular nanosystems in solution.
Kovalenko, A.
core   +2 more sources

Urinary Recovery of Salicylamide as Its Glucuronide in Liver Disease [PDF]

, 1962
An attempt was made to establish the method for the estimation of glucuronide formation in vivo using salicylamide and further to study the alteration in the glucuronide formation in liver disease. The results were as follows: 1.
Taketa, Kazuhisa
core   +1 more source

Genome-wide analysis of the UDP-glucose dehydrogenase gene family in Arabidopsis, a key enzyme for matrix polysaccharides in cell walls [PDF]

, 2007
Arabidopsis cell walls contain large amounts of pectins and hemicelluloses, which are predominantly synthesized via the common precursor UDP-glucuronic acid.
Klinghammer, Michaela, Tenhaken, Raimund
core   +1 more source

Roles of Predicted Glycosyltransferases in the Biosynthesis of the Rhizobium etli CE3 O Antigen [PDF]

, 2013
The Rhizobium etli CE3 O antigen is a fixed-length heteropolymer. The genetic regions required for its synthesis have been identified, and the nucleotide sequences are known.
Noel, K. Dale, Ojeda, Kristylea J., Simonds, Laurie   +2 more
core   +2 more sources