Results 41 to 50 of about 15,247 (253)

Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

Parasites & Vectors, 2022
Background Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA).
Yang-Yuan Qiu, Qiao-Cheng Chang, Jun-Feng Gao, Ming-Jia Bao, Hai-Tao Luo, Jin-Ho Song, Sung-Jong Hong, Rui-Feng Mao, Yun-Yi Sun, Ying-Yu Chen, Ming-Yuan Liu, Chun-Ren Wang, Xiao-Lei Liu   +12 more
doaj   +1 more source

Pyrosequencing-based analysis reveals a novel capsular gene cluster in a KPC-producing Klebsiella pneumoniae clinical isolate identified in Brazil [PDF]

, 2012
Background: An important virulence factor of Klebsiella pneumoniae is the production of capsular polysaccharide (CPS), a thick mucus layer that allows for evasion of the host's defense and creates a barrier against antibacterial peptides.
Almeida, Luiz Gonzaga P., Gales, Ana Cristina, Gerber, Alexandra L., Goda Zuleta, Luiz Fernando, Nicolas, Marisa Fabiana, Pelisson, Marsileni, Pereira Ramos, Pablo Ivan, Picão, Renata Cristina, Vasconcelos, Ana Tereza R., Vespero, Eliana Carolina   +9 more
core   +2 more sources

Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]

, 1990
An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Ballanyi, Beam, Bretag, Cook, Engel, Escande, Fosset, Hamilton, Huang, Iaizzo, Lehmann-Horn, Quasthoff, Ruff, Ruff, R�del, R�del, Sanguinetti, Spuler, Sturgess, Tanabe   +19 more
core   +1 more source

Causal relationship between plasma metabolites and carpal tunnel syndrome risk: evidence from a mendelian randomization study

Frontiers in Molecular Biosciences
BackgroundCarpal tunnel syndrome (CTS) is a common symptom of nerve compression and a leading cause of pain and hand dysfunction. However, the underlying biological mechanisms are not fully understood.
Wenbao Wu, Daofeng Fan, Chong Zheng, Binfu Que, Qing qing Lian, Yangui Chen, Rui Qiu   +6 more
doaj   +1 more source

Metabolomic effects of CeO2, SiO2 and CuO metal oxide nanomaterials on HepG2 cells

Particle and Fibre Toxicology, 2017
Background To better assess potential hepatotoxicity of nanomaterials, human liver HepG2 cells were exposed for 3 days to five different CeO2 (either 30 or 100 μg/ml), 3 SiO2 based (30 μg/ml) or 1 CuO (3 μg/ml) nanomaterials with dry primary particle ...
Kirk T. Kitchin, Steve Stirdivant, Brian L. Robinette, Benjamin T. Castellon, Xinhua Liang   +4 more
doaj   +1 more source

Occurrence of Hydroxytyrosol, Tyrosol and Their Metabolites in Italian Cheese

Molecules, 2023
Tyrosol (T) and hydroxytyrosol (HT) are phenyl alcohol polyphenols with well-recognized health-promoting properties. They are widely diffused in several vegetables, especially in olive products (leaves, fruits and oil).
Danilo Giusepponi, Carolina Barola, Elisabetta Bucaletti, Simone Moretti, Fabiola Paoletti, Andrea Valiani, Raffaella Branciari, Roberta Galarini   +7 more
doaj   +1 more source

Glycosaminoglycans in the human cornea: age-related changes [PDF]

, 2015
AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia, Cavallotti, Carlo, De Paolis, Giulio, Pacella, Elena, Pacella, Fernanda, Parisella, Francesca Romana, Turchetti, Paolo   +6 more
core   +2 more sources

Evaluation of the efficiency of the hepatoprotector glucuronate in toxic hepatitis of various etiology

Вестник анестезиологии и реаниматологии
The objective was to study the effectiveness of the use of hepatoprotector glucuronate at the early stage of intensive therapy of toxic hepatitis of various etiologies.Materials and methods.
R. N. Akalaev, A. M. Khadjibaev, A. A. Stopnitskiy, D. B. Tulyaganov, U. R. Kamilov, M. K. Saidova   +5 more
doaj   +1 more source

Overexpression of UDP-glucose dehydrogenase from Larix gmelinii enhances growth and cold tolerance in transgenic Arabidopsis thaliana

Biologia Plantarum, 2017
Uridine diphosphate glucose dehydrogenase (UGDH) plays an important role in biosynthesis of hemicellulose by catalyzing oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronate (UDP-GlcA), a key sugar nucleotide involved in biosynthesis of the plant cell ...
N. N. Li, L. Chen, X. H. Li, Q. Li, W. B. Zhang, K. Takechi, H. Takano, X. F. Lin   +7 more
doaj   +1 more source

Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community

Cardiovascular Diabetology, 2022
Background New biomarkers to identify cardiovascular disease (CVD) risk earlier in its course are needed to enable targeted approaches for primordial prevention.
Daniel Gonzalez Izundegui, Patricia E. Miller, Ravi V. Shah, Clary B. Clish, Maura E. Walker, Gary F. Mitchell, Robert E. Gerszten, Martin G. Larson, Ramachandran S. Vasan, Matthew Nayor   +9 more
doaj   +1 more source