Results 81 to 90 of about 15,247 (253)

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

, 2014
<b>Background:</b>  Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC ...
Atrih, A., Barton, G., Bray, S. E., Fleming, S., Huang, J. T.-J., Lamont, D. J., Mudaliar, M. A. V., Nabi, G., Zakikhani, P.   +8 more
core   +4 more sources

Transcriptomic Responses of the Marine Diatom Phaeodactylum tricornutum to High Carbon and Low Nitrogen Stress

Ecology and Evolution, Volume 16, Issue 1, January 2026.
To elucidate the integrated transcriptional mechanisms underlying diatom acclimation to coupled carbon–nitrogen (CN) imbalance, we employed RNA sequencing (RNA‐Seq) to characterize the global transcriptional response of the model diatom Phaeodactylum tricornutum to high CO2 (~2000 μatm) and low nitrogen (10% of nitrogen concentration in f/2 medium ...
Yi Zhang, Jiawen Duan, Yimeng Zheng, Xiaoqi Chen, Chenhui Li, Zhenyu Xie, Aiyou Huang   +6 more
wiley   +1 more source

Selenium‐Enriched Matcha Ameliorates Alcohol‐Induced Liver Injury by Modulating Cytochrome P450 Expression in Mice

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Selenium is an essential trace element for human health, and the selenium content in selenium‐enriched matcha meets the official criteria for selenium‐enriched foods in China. In the present work, hepatoprotective effects of selenium‐enriched matcha against alcohol‐induced liver injury were systematically investigated, and its mechanism was ...
Zhuo‐Wen Su, Xiao‐Hua Yang, Hua‐Feng Zhang, Lu Li, Si‐Yu Deng, Zhi‐Chen Mo   +5 more
wiley   +1 more source

Untargeted Metabolomics Reveal the Protective Effect of Bone Marrow Mesenchymal Stem Cell Transplantation Against Ovariectomy-Induced Osteoporosis in Mice

Cell Transplantation, 2022
Bone marrow mesenchymal stem cell transplantation (BMSCT) is a potential treatment for osteoporosis, capable of contributing to bone tissue repair. BMSCT has demonstrated osteoinductive effects and the ability to regulate microenvironmental metabolism ...
Weizhou Wang, Yanghao Wang, Jun Hu, Hao Duan, Zhihua Wang, Liang Yin, Fei He   +6 more
doaj   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

The FEBS Journal, Volume 293, Issue 2, Page 492-513, January 2026.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone, Linley R. Schofield, Patrick J. B. Edwards, Andrew J. Sutherland‐Smith, Ron S. Ronimus   +4 more
wiley   +1 more source

Synthesis of Uridine Diphosphate-Glucuronic Acid

Chemical and Pharmaceutical Bulletin, 1960
Uridine 5'-phosphoramidate (I) was allowed to react with α-glucuronic acid 1-phosphate (II), and α-uridine diphosphate glucuronic acid (α-UDPGA) (III) was isolated from the reaction mixture by ion exchange chromatography. Likewise, β-UDPGA (V) was produced from (I) and β-glucuronic acid 1-phosphate (IV).
M, HONJO, Y, FURUKAWA, K, IMAI, H, MORIYAMA, K, TANAKA   +4 more
openaire   +4 more sources

Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 328-345, January 2026.
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat, Adam Jozwiak, Ilana Rogachev, Elinor A. Sharon, Sagit Meir, Ashok P. Giri, Asaph Aharoni   +6 more
wiley   +1 more source

RNASET2 Deficiency Induces Hepatocellular Carcinoma Metastasis through Cholesterol‐Triggered MET Activation

Advanced Science
Metastasis remains a significant challenge in the treatment of hepatocellular carcinoma (HCC). The role of ribonuclease T2 (RNASET2) in HCC is still uncertain, although it has been reported to have contradictory effects on some cancers.
Yanquan Xu, Yu Chen, Jiangang Zhang, Jingchun Wang, Shuai Yang, Huakan Zhao, Lei Wu, Juan Lei, Yu Zhou, Jin Peng, Lu Jiang, Qian Chen, Rong Xin, Jianyun Zhou, Yongsheng Li   +14 more
doaj   +1 more source

Charge neutralization and β-elimination cleavage mechanism of family 42 L-rhamnose-α-1,4-D-glucuronate lyase revealed using neutron crystallography [PDF]

, 2022
Naomine Yano, Tatsuya Kondo, Katsuhiro Kusaka, Taro Yamada, T. Arakawa, Tatsuji Sakamoto, Shinya Fushinobu   +6 more
openalex   +1 more source

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis

JOR SPINE, Volume 8, Issue 4, December 2025.
Matrix and cell‐associated proteoglycans are important tissue‐stabilizing, weight‐bearing, and tension‐resisting proteins in the intervertebral disc. Their glycosaminoglycan components have growth factor binding and cell‐instructive properties that allow cells to regulate tissue composition and function.
James Melrose
wiley   +1 more source