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Carnitine and glucuronic acid conjugates of pivalic acid

Xenobiotica, 1985
The [1-14C]pivaloyloxyethyl ester of methyldopa administered to man and cynomolgus monkeys resulted in the elimination in the urine of 14C-pivalic acid metabolites. Pivaloyl glucuronide and pivaloyl carnitine were identified as the major radioactive urinary metabolites in monkey urine and human urine, respectively. N.m.r.
C. A. H. Duncan   +7 more
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Glucuronic acid conjugates

Journal of Chromatography B: Biomedical Sciences and Applications, 1998
The methods of assay in body fluids of 1-beta-alkyl, 1-beta-phenyl and 1-beta-acyl glucuronic acids ("glucuronide conjugates") have been reviewed. Most of the 78 references cited (from the literature of the period 1990-1997) concern the glucuronide conjugates of drug metabolites, and these have been considered, for reasons of accessibility, within ...
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Glucuronic acid cycle in arterial tissue

Zeitschrift für die gesamte experimentelle Medizin einschließlich experimentelle Chirurgie, 1970
The presence of all enzymatic steps of the glucuronic acid pathway could be demonstrated in arteries of various species.14C-D-glucose was converted into14C-D-glucuronic acid; 6-14C-D-glucuronic acid was decarboxylated to14CO2 and U-14C-D-glucuronic acid was transformed into14C-xylitol. NADP-L-xylulose oxidoreductase (E.C.
R Sanwald, E Ritz
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Determination of glucuronic acid by naphthoresorcinol

Analytical Biochemistry, 1964
Abstract A modified naphthoresorcinol procedure is described for the quantitative determination of glucuronic acid. A sensitive and stable naphthoresorcinol solution yields precise and reproducible results.
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GLUCURONIC ACID IN THE THERAPY OF PSORIASIS

Archives of Dermatology, 1954
Since glucuronic acid has been synthesized, a renewed interest has been shown in its physiological role, particularly in its influence in the so-called collagen diseases. Peterman was the first to point out a glucuronic acid deficiency in rheumatoid arthritis, as well as good therapeutic results in this disease with the calcium, potassium, or sodium ...
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D-Glucuronic Acid in Metabolism

1953
Publisher Summary In the fields of biochemistry and pharmacology, interest in D -glucuronic acid has centered round the part it plays in the metabolism of drugs and other foreign organic compounds. While the ability of the organism to synthesize D -glucuronic acid in response to the administration of such compounds is truly remarkable, the extent ...
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Effects of Ionizing Radiations on Glucuronic Acid

Radiation Research, 1970
The effects of radical scavengers and solute concentration indicate that the degradation of glucuronic acid by60 Co γ-irradiation is mainly due to OH radicals. Pulse radiolysis demonstrates no significant reaction of sodium glucuronate with $e_{{\rm aq}}^{-}(k_{2}\leq 10^{6}\ M^{-1}\ \text{second}^{-1})$, but a facile reaction with OH radicals ( $k_{2}\
G. O. Phillips, N. W. Worthington
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