Results 81 to 90 of about 59,666 (243)

Chemical structure and antioxidant activity of a new exopolysaccharide produced from Micrococcus luteus

Journal of Genetic Engineering and Biotechnology, 2014
An exopolysaccharide (EPS) reaching a maximum of 13 g/L was isolated from Micrococcus luteus by ethanol precipitation. The crude EPS was purified by chromatography on DEAE-cellulose and Sephacryl S-200, affording a polysaccharide active fraction (AEP ...
Mohsen Mohamed Selim Asker, Osama Hamed EL Sayed, Manal Gomaa Mahmoud, Mohamed Fawzy Ramadan   +3 more
doaj   +1 more source

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

Nature Communications, 2020
UDP-glucuronic acid is a component of the extracellular matrix. Here, the authors report biallelic variants in the gene encoding UDP-Glucose 6-Dehydrogenase (UGDH) in individuals affected by developmental epileptic encephalopathies that impair UGDH ...
Holger Hengel, Célia Bosso-Lefèvre, George Grady, Emmanuelle Szenker-Ravi, Hankun Li, Sarah Pierce, Élise Lebigot, Thong-Teck Tan, Michelle Y. Eio, Gunaseelan Narayanan, Kagistia Hana Utami, Monica Yau, Nader Handal, Werner Deigendesch, Reinhard Keimer, Hiyam M. Marzouqa, Meral Gunay-Aygun, Michael J. Muriello, Helene Verhelst, Sarah Weckhuysen, Sonal Mahida, Sakkubai Naidu, Terrence G. Thomas, Jiin Ying Lim, Ee Shien Tan, Damien Haye, Michèl A. A. P. Willemsen, Renske Oegema, Wendy G. Mitchell, Tyler Mark Pierson, Marisa V. Andrews, Marcia C. Willing, Lance H. Rodan, Tahsin Stefan Barakat, Marjon van Slegtenhorst, Ralitza H. Gavrilova, Diego Martinelli, Tal Gilboa, Abdullah M. Tamim, Mais O. Hashem, Moeenaldeen D. AlSayed, Maha M. Abdulrahim, Mohammed Al-Owain, Ali Awaji, Adel A. H. Mahmoud, Eissa A. Faqeih, Ali Al Asmari, Sulwan M. Algain, Lamyaa A. Jad, Hesham M. Aldhalaan, Ingo Helbig, David A. Koolen, Angelika Riess, Ingeborg Kraegeloh-Mann, Peter Bauer, Suleyman Gulsuner, Hannah Stamberger, Alvin Yu Jin Ng, Sha Tang, Sumanty Tohari, Boris Keren, Laura E. Schultz-Rogers, Eric W. Klee, Sabina Barresi, Marco Tartaglia, Hagar Mor-Shaked, Sateesh Maddirevula, Amber Begtrup, Aida Telegrafi, Rolph Pfundt, Rebecca Schüle, Brian Ciruna, Carine Bonnard, Mahmoud A. Pouladi, James C. Stewart, Adam Claridge-Chang, Dirk J. Lefeber, Fowzan S. Alkuraya, Ajay S. Mathuru, Byrappa Venkatesh, Joseph J. Barycki, Melanie A. Simpson, Saumya S. Jamuar, Ludger Schöls, Bruno Reversade   +84 more
doaj   +1 more source

Partial characterization and anticoagulant activity of a heterofucan from the brown seaweed Padina gymnospora [PDF]

, 2005
The brown algae Padina gymnospora contain different fucans. Powdered algae were submitted to proteolysis with the proteolytic enzyme maxataze. The first extract of the algae was constituted of polysaccharides contaminated with lipids, phenols, etc ...
Alves, L.g., Chavante, Suely Ferreira, Leite, E.l., Marques, C.t., Queiroz, K.c.s. de, Rocha, Hugo Alexandre Oliveira, Santos, M.g.l., Silva, T.m.a.   +7 more
core   +4 more sources

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Novel GH115 xylan α-1,2-glucuronidases with distinct preferences for xylan-derived oligomers and polymers. [PDF]

Protein Sci
Abstract Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin‐dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's ...
Leontakianakou S, Le SB, Sundin A, Jasilionis A, Nguyen GS, Nordborg A, Gottumukkala LD, Grey C, Lewin AS, Karlsson EN.   +9 more
europepmc   +2 more sources

Demonstration of chondroitin sulfates degrading endo-β-glucuronidase activity in rabbit liver [PDF]

, 1985
Reduced chondroitin sulfate was incubated with rabbit liver extracts followed by reduction once more with sodium [3H]borohydride, and then passed through a Sephadex G-100 column.
Takagaki, Keiichi, Nakamura, Toshiya, Majima, Mitsuo, Endo, Masahiko   +3 more
core   +2 more sources

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, EarlyView.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source

Subacute Assessment of the Toxicity and Antidepressant-Like Effects of Origanum Majorana L. Polyphenols in Swiss Albino Mice

Molecules, 2020
Origanum majorana L. is a plant commonly used in folk medicine to treat depression and several neurological disorders. This study aims to evaluate the antidepressant-like effect of the Origanum majorana L. polyphenols (OMP) obtained from the aerial parts
Amal Amaghnouje, Hamza Mechchate, Imane Es-safi, Smahane Boukhira, Ali S. Aliqahtani, Omar M. Noman, Fahd A. Nasr, Raffaele Conte, Anna Calarco, Dalila Bousta   +9 more
doaj   +1 more source

Dietary Supplementation with Soluble Plantain Non-Starch Polysaccharides Inhibits Intestinal Invasion of Salmonella Typhimurium in the Chicken [PDF]

, 2014
Soluble fibres (non-starch polysaccharides, NSP) from edible plants but particularly plantain banana (Musa spp.), have been shown in vitro and ex vivo to prevent various enteric pathogens from adhering to, or translocating across, the human intestinal ...
A Alnaqdy, A Cencic, A Currie, A Kato, A Tahoun, Alastair J. M. Watson, Anne-Marie Salisbury, Barry J. Campbell, BC Yang, Bryony N. Parsons, C Austin, C Casteleyn, Carol L. Roberts, CL Roberts, CL Roberts, CR Braden, D Mohnen, David O'Brien, DF Gray, F Piras, FJ Gormley, GS Withanage, H Kitagawa, Hannah L. Simpson, HM Martin, HN Englyst, HV Murugkar, J Willamil, JH Lee, Johan D. Söderholm, Jonathan M. Rhodes, Jonathan M. Williams, JS Lim, K Van Deun, KG Steube, L Chappell, L Heres, LT Sunkara, M Dick-Perez, M Dubois, MA Jepson, MA Jones, MA O'Neill, Michael Hensel, MJR Clark, Niamh O'Kennedy, P Flanagan, P Perrone, P Sansonetti, PA Barrow, Paul Wigley, PEW Morrissey, PR Watson, R Merle, RP Ferraris, S Keely, SC Fry, SD de Oliveira, SL Gardner, SM Bueno, Stephen C. Fry, Suzie Humphrey, WA Awad, YO Fasina, ZA Popper, Åsa V. Keita   +65 more
core   +6 more sources

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source