Results 101 to 110 of about 2,542,969 (232)

Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides by a Covalent Catch‐and‐Release Approach

open access: yesAngewandte Chemie, Volume 138, Issue 36, 1 September 2026.
A glycan having a hydrazide tag enables chemoenzymatic synthesis of HS oligosaccharides. The hydrazide can, under mild acidic conditions, react with an aldehyde‐containing resin to give an immobilized hydrazone that is stable under neutral conditions, allowing washing. The product can be released by transiminolysis using aqueous hydroxylamine to give a
Francesco Palmieri   +4 more
wiley   +2 more sources

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.

open access: yesPLoS Genetics, 2019
Pathological phosphorylated TDP-43 protein (pTDP) deposition drives neurodegeneration in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP).
Nicole F Liachko   +6 more
doaj   +1 more source

A quantitative study of glucuronic acid excretion.

open access: yes, 1938
Since the discovery by Wiedemann in 1876 of a peculiar acid in the urine of dogs following camphor feeding, and the subsequent identification of this acid by Schmiedeberg in 1879, much interest has centred sporadically about the nature and physiological ...
Maughan, George B.
core  

Multiplexed Engineering of Disease Resistance and Lodging Tolerance in Wheat Via a Single Xylan Modifying Glycosyltransferase

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Breeding crops with robust disease resistance often compromises yield, a persistent challenge in agricultural improvement. We report that modifying cell wall architecture through a xylan‐specific glycosyltransferase successfully breaks this trade‐off in wheat.
Shufang Sun   +6 more
wiley   +1 more source

Rapid Determination of the Monosaccharide Composition and Contents in Tea Polysaccharides from Yingshuang Green Tea by Pre-Column Derivatization HPLC

open access: yesJournal of Chemistry, 2016
A pre-column derivatization high-performance liquid chromatography (HPLC) method was developed and optimized to characterize and quantify the monosaccharides present in tea polysaccharides (TPS) isolated from Yingshuang green tea.
Yujie Ai   +6 more
doaj   +1 more source

Electrolytic Preparation of Glucuronic Acid from Glucose

open access: yes, 1938
The object of this work was to develop an efficient laboratory method for the preparation of glucuronic acid. That compound is of particular interest to the biological chemist on account of the unusual oxidation of glucose in the process of its ...
Leutgoeb, Rosalia Aloisia
core  

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak   +10 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Conversion of Glucuronic Acid Glycosides to Novel Bicyclic β-Lactams

open access: yes, 2016
Methodology for the conversion of glucuronic acid glycosides to novel bicyclic β-lactams is reported. Using this strategy, we prepared two novel templates suitable for use in combinatorial chemistry strategies for the construction of a number of ...
Timothy B. Durham (1698085)   +1 more
core   +2 more sources

Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans

open access: yesBiomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT RU 58841 is a nonsteroidal antiandrogen, developed for the treatment of androgen‐dependent conditions. This study aimed to characterize the human metabolism of RU 58841 for the first time and to assess its systemic exposure following topical administration.
Aylin Okutan   +4 more
wiley   +1 more source

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