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Mucopolysaccharidosis VII: ?-Glucuronidase deficiency

Human Genetics, 1974
An 18-month-old female showed a markedly decreased activity of the lysosomal enzyme β-D-glucuronidase in cultured fibroblasts, leucocytes, and serum. In obligate heterozygotes, the serum and leucocyte β-D-glucuronidase activity was decreased to approximately 50% of the control values. Clinically, the patient had a mild facial dysmorphism reminiscent of
J, Gehler   +5 more
openaire   +2 more sources

Cytochemical Localization of β-Glucuronidase

Nature, 1950
APPLYING histochemical techniques devised by Friedenwald and Becker1, it was found2 that in normal male mouse liver (Fig. 1) and kidney, β-glucuronidase activity is mainly confined to the mitochondria. It was considered that the rise in glucuronidase activity shown by biochemical methods to occur in these organs when repair has commenced subsequent to ...
J G, CAMPBELL, G A, LEVVY
openaire   +2 more sources

Beta-Glucuronidase

Science, 1948
L D, Odell, W H, Fishman, W R, Hepner
openaire   +2 more sources

Genetic Regulation of Mammalian Glucuronidase

1978
Publisher Summary Glucuronidase is useful in dividing mutations into four categories: structural genes, regulatory genes, processing genes, and temporal genes. This chapter discusses regulatory genes that affect the synthesis of mouse kidney glucuronidase in response to androgens.
Swank, R T   +8 more
openaire   +2 more sources

The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase.

International Journal of Biological Macromolecules, 2019
Chengpeng Sun   +13 more
semanticscholar   +1 more source

Beta-glucuronidase

1991
Dietmar Schomburg, Margit Salzmann
openaire   +1 more source

Histochemical Staining of β-Glucuronidase and Its Spatial Quantification.

Methods in molecular biology, 2017
Chloé Béziat   +2 more
semanticscholar   +1 more source

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