Results 1 to 10 of about 31,662 (260)

ATM and GLUT1-S490 phosphorylation regulate GLUT1 mediated transport in skeletal muscle. [PDF]

open access: yesPLoS ONE, 2013
The glucose and dehydroascorbic acid (DHA) transporter GLUT1 contains a phosphorylation site, S490, for ataxia telangiectasia mutated (ATM). The objective of this study was to determine whether ATM and GLUT1-S490 regulate GLUT1.L6 myoblasts and mouse ...
Stanley Andrisse   +9 more
doaj   +5 more sources

Greasy GLUT1 maintains glioblastoma malignancy [PDF]

open access: yesMolecular & Cellular Oncology, 2021
How cancer cells absorb enough glucose to support their rapid growth is poorly understood. We have recently demonstrated that palmitoyl transferase DHHC9 palmitoylates glucose transporter GLUT1 at Cys207 to maintain GLUT1 plasma membrane localization ...
Caiyun Liu, Xinjian Li
doaj   +3 more sources

GLUT1 sensitizes tumor cells to EGFR-TKIs by binding with activated EGFR and regulating its downstream signaling pathways [PDF]

open access: yesCell Communication and Signaling
Background We have previously demonstrated that GLUT1 can interact with phosphorylated EGFR and has an oncogenic role in lung cancer. Here, we aim to investigate their binding region and its signaling pathways.
Zhangrong Xie   +5 more
doaj   +2 more sources

Oncolytic Avian Reovirus σA-Modulated Upregulation of the HIF-1α/C-myc/glut1 Pathway to Produce More Energy in Different Cancer Cell Lines Benefiting Virus Replication

open access: yesViruses, 2023
Our previous reports proved that the structural protein σA of avian reovirus (ARV) is an energy activator which can regulate cellular metabolism that is essential for virus replication.
Chao-Yu Hsu   +8 more
doaj   +1 more source

BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1

open access: yesCancer Biology & Therapy, 2023
Hepatocellular carcinoma (HCC) is a grievous tumor with an increasing incidence worldwide. Basic transcription factor 3 (BTF3) is discovered to regulate the expression of glucose transporter 1 (GLUT1), which benefits glycolysis, a momentous signature of ...
Peng Wang   +5 more
doaj   +1 more source

A novel association between Bmi-1 protein expression and the SUVmax obtained by 18F-FDG PET/CT in patients with gastric adenocarcinoma

open access: yesOpen Life Sciences, 2022
This study aimed to examine B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) in gastric adenocarcinoma (GAC) and its association with the maximal standard uptake value (SUVmax) of preoperative fluorine-18-fludeoosyglucose positron
Guo Ying, Zhang Li, Ma Qingjie
doaj   +1 more source

Tg(Δ113p53:cmyc) Transgene Upregulates glut1 Expression to Promote Zebrafish Heart Regeneration

open access: yesJournal of Cardiovascular Development and Disease, 2023
The heart switches its main metabolic substrate from glucose to fatty acids shortly after birth, which is one of reasons for the loss of heart regeneration capability in adult mammals.
Zimu Tang   +3 more
doaj   +1 more source

Understanding the Spectrum of SLC2A1-Associated Disorders

open access: yesPediatric Neurology Briefs, 2017
Investigators from the Danish Epilepsy Center the frequency of SLC2A1 mutations in a cohort of patients with different types of epilepsies.
Marytery Fajardo, Melissa L. Cirillo
doaj   +1 more source

Investigation of GLUT1, HIF1α and TBX21 Gene Polymorphisms in Laryngeal Cancer

open access: yesTurkish Archives of Otorhinolaryngology, 2018
Objective: We aimed to investigate the association of the frequency of three single-nucleotide polymorphisms [glucose transporter isoform 1 (GLUT1) reference single-nucleotide polymorphism (rs) 710218, hypoxia-inducible factor 1 alpha (HIF1α) rs11549465,
Cihan Uslu   +3 more
doaj   +1 more source

Prognostic value of glucose transporter proteins-1 (GLUT1) in breast carcinoma

open access: yesLibyan Journal of Medicine, 2023
Several studies have reported increased glucose transporters (GLUT) expression in different cancer types, including breast cancer. The primary purpose of this study is to examine GLUT1 immunoexpression in breast cancer patients in Saudi Arabia and to ...
Mehenaz Hanbazazh   +3 more
doaj   +1 more source

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