Results 111 to 120 of about 47,601 (323)

3D‐Printed Protein Models as an Educational Tool in Biochemistry Outreach

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT The abstract and complex nature of molecular biology often presents significant challenges for students at all levels of study. Traditional teaching methods, such as the use of 2D diagrams, may not fully convey the intricacies of these topics, leading to difficulties in comprehension and engagement. This study aimed to introduce 3D‐printed and
Oliver Osborne, Siobhan Clennell, Shaun K. Bremner‐Hart   +2 more
wiley   +1 more source

Functional studies of threonine 310 mutations in Glut1: T310I is pathogenic, causing Glut1 deficiency.

The Journal of biological chemistry, 2004
We have previously reported on a patient with the Glut1 deficiency syndrome (Online Mendelian Inheritance in Man number 606777) carrying a heterozygous T310I missense mutation in the GLUT1 gene (Klepper, J., Wang, D., Fischbarg, J., Vera, J. C., Jarjour, I. T., O'Driscoll, K. R., and De Vivo, D. C. (1999) Neurochem. Res. 24, 587-594).
Dong, Wang, Juan M, Pascual, Pavel, Iserovich, Hong, Yang, Li, Ma, Kunyan, Kuang, Felipe A, Zuniga, Ruo Peng, Sun, Kavita M, Swaroop, Jorge, Fischbarg, Darryl C, De Vivo   +10 more
openaire   +2 more sources

Antimutagenic 1,4-Dihydropyridine AV-153 Normalizes Expression of GLUT1, GLUT4, INOS, PARP1, and Gamma H2AX Histone in Myocardium of Rats with Streptozotocin Model of Diabetes Mellitus [PDF]

, 2023
Evita Rostoka, Sergejs Isajevs, Jeļizaveta Sokolovska, Г. Дубурс, Nikolajs Sjakste   +4 more
openalex   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Therapeutic strategies for glucose transporter 1 deficiency syndrome

Annals of Clinical and Translational Neurology, 2019
Proper development and function of the mammalian brain is critically dependent on a steady supply of its chief energy source, glucose. Such supply is mediated by the glucose transporter 1 (Glut1) protein. Paucity of the protein stemming from mutations in
Maoxue Tang, Sarah H. Park, Darryl C. De Vivo, Umrao R. Monani   +3 more
doaj   +1 more source

GLUT1 érythrocytaire [PDF]

médecine/sciences, 2008
Amélie Montel-Hagen, Sandrina Kinet, Nicolas Manel, Cédric Mongellaz, Rainer Prohaska, Jean-Luc Battini, Jean Delaunay, Marc Sitbon, Naomi Taylor   +8 more
openaire   +1 more source

Glucose transporter Glut1 controls diffuse invasion phenotype with perineuronal satellitosis in diffuse glioma microenvironment [PDF]

, 2020
Masafumi Miyai, Tomohiro Kanayama, Fuminori Hyodo, Takamasa Kinoshita, Takuma Ishihara, Hideshi Okada, Hiroki Suzuki, Shigeo Takashima, Zhiliang Wu, Yuichiro Hatano, Yusuke Egashira, Yukiko Enomoto, Noriyuki Nakayama, Akio Soeda, Hirohito Yano, Akihiro Hirata, Masayuki Niwa, Shigeyuki Sugie, Takashi Mori, Yoichi Maekawa, Toru Iwama, Masayuki Matsuo, Akira Hara, Hiroyuki Tomita   +23 more
openalex   +1 more source

Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard, Blandine Dozières‐Puyravel, Katia Geraldes, Céline Perrot, Virginie Quéméner, Estelle Goujon, Pierre Truchy, Hala Nasser, François‐Xavier Mauvais, Marion Danse, Stéphane Auvin   +10 more
wiley   +1 more source