Results 121 to 130 of about 31,662 (260)

Identification of an Amino Acid Residue That Lies between the Exofacial Vestibule and Exofacial Substrate-binding Site of the Glut1 Sugar Permeation Pathway [PDF]

, 1997
Mike Mueckler, Carol M. Makepeace
openalex   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Disruption of GLUT1 glucose carrier trafficking in L6E9 and Sol8 myoblasts by the phosphatidylinositol 3-kinase inhibitor wortmannin [PDF]

, 1995
Perla Kaliman, Francesc Viñals, Xavier Testar, Manuel Palacı́n, António Zorzano   +4 more
openalex   +1 more source

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Cyclic Adenosine 3′,5′-Monophosphate Regulates GLUT4 and GLUT1 Glucose Transporter Expression and Stimulates Transcriptional Activity of the GLUT1 Promoter in Muscle Cells* [PDF]

, 1997
Francesc Viñals, Josep Ferré, César Fandos, Tomàs Santalucı́a, Xavier Testar, Manuel Palacı́n, António Zorzano   +6 more
openalex   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice [PDF]

, 1998
Garret J. ETGEN, William J. ZAVADOSKI, Geoffrey D. Holman, E. Michael GIBBS   +3 more
openalex   +1 more source

Síndrome de deficiencia de GLUT1 y COVID-19

Endocrinología, Diabetes y Nutrición, 2021
Arrieta Blanco, Francisco, Bélanger Quintana, Amaya, Bengoa Rojano, Nuria, Stanescu, Sinziana, MartinezPardo, Mercedes   +4 more
openaire   +4 more sources

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen, Annelii Ny, Daniëlle Copmans, Jana Tits, Kenichi Kamata, Eva Gielis, Kevin Longin, Jo Sourbron, Peravina Thergarajan, Tracie Huey‐Lin Tan, Idrish Ali, Nigel C. Jones, Terence J. O'Brien, Mastura Monif, Bridgette D. Semple, Christine Germeys, Benedetta Frizzi, Virginia Minniti, Sebastian Perrone, Carole L. Linster, Ilaria Elia, Ludo Van Den Bosch, Bruno P. A. Cammue, Arnout Voet, Lieven Lagae, Peter de Witte   +25 more
wiley   +1 more source

Lactogenic Hormones Cause Glycosylation-Independent Targeting of the GLUT1 Glucose Transporter of Mammary Epithelial Cells to a Subcompartment of cis- and/or medial-Golgi [PDF]

, 1999
Peter M. Haney
openalex   +1 more source