Results 141 to 150 of about 47,601 (323)

Inhibition of adenoid cystic carcinoma cell proliferation and migration through autophagy inhibition via GLUT1 knockdown [PDF]

, 2023
Kan Liu, Jin-Long Zhu, Yang‐Yang Bao, Fang Jin, Shui‐Hong Zhou, Jun Fan   +5 more
openalex   +1 more source

Mutant p53 Regulates Pyruvate Dehydrogenase Kinase 1 (PDK1) to Promote Proliferation and Migration in Breast Cancer

Cancer Science, EarlyView.
PDK1 is a direct transcriptional repression target of wtp53 and mutp53 can sustain its own stability by upregulating PDK1 in breast cancer. ABSTRACT Tumor suppressor p53 is the most frequently mutated gene in cancers. Mutations in p53 not only result in the loss of its classical tumor‐suppressive functions but also confer new oncogenic properties.
Yan Ye, Zuli Ou, Canling Li, Qingyu Liao, Qian Zeng, Xiaoqian Ju, Dian Zhang, Yu Wei, Xiang Zhang, Tao Zhang, Kejia Wu   +10 more
wiley   +1 more source

Table S1 from Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in <i>KRAS</i>-Mutant Cancer Cells

, 2023
Johanna Erber, Joachim D. Steiner, Jörg Isensee, Leonard A. Lobbes, André Toschka, Filippo Beleggia, Anna Schmitt, Rainer Kaiser, Florian Siedek, Thorsten Persigehl, Tim Hucho, Hans Christian Reinhardt   +11 more
openalex   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

The protective role of endothelial GLUT1 in ischemic stroke

Brain and Behavior
Objective To provide thorough insight on the protective role of endothelial glucose transporter 1 (GLUT1) in ischemic stroke. Methods We comprehensively review the role of endothelial GLUT1 in ischemic stroke by narrating the findings concerning ...
Qiwei Peng, Weiqi Zeng
doaj   +1 more source

Table S2 from GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy

, 2023
Pierre‐Benoit Ancey, Caroline Contat, Gaël Boivin, Silvia Sabatino, Justine Pascual, Nadine Zangger, Jean Yannis Perentes, Solange Peters, E. Dale Abel, David G. Kirsch, Jeffrey C. Rathmell, Marie‐Catherine Vozenin, Etienne Meylan   +12 more
openalex   +1 more source

Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways

Cell Proliferation, EarlyView.
IL10_ApoEVs, generated during IL‐10‐induced fibroblast apoptosis, reprogram fibroblast metabolism and inhibit fibrosis to promote scarless skin healing. By enhancing mitochondrial OXPHOS, suppressing glycolysis, and downregulating Hedgehog signaling, IL10_ApoEVs shift collagen deposition toward regenerative type III collagen, offering a novel strategy ...
Yang Zou, Jinglun Zhang, Wenxuan Mao, Shuting Jiang, Cheng Xu, Jiayi Meng, Heng Dong, Yongbin Mou   +7 more
wiley   +1 more source

Table S5 from GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy

, 2023
Pierre‐Benoit Ancey, Caroline Contat, Gaël Boivin, Silvia Sabatino, Justine Pascual, Nadine Zangger, Jean Yannis Perentes, Solange Peters, E. Dale Abel, David G. Kirsch, Jeffrey C. Rathmell, Marie‐Catherine Vozenin, Etienne Meylan   +12 more
openalex   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Contribution of reactive oxygen species to the regulation of glut1 in two hemopoietic cell lines differing in cytokine sensitivity

, 2004
Diana Fiorentini, Cecilia Prata, Tullia Maraldi, Laura Zambonin, Laura Bonsi, Gabriele Hakim, Laura Landi   +6 more
openalex   +2 more sources