Results 151 to 160 of about 47,601 (323)

Table S4 from GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy

open access: gold, 2023
Pierre‐Benoit Ancey   +12 more
openalex   +1 more source

Clinical and genetic landscape of epilepsies with absence seizures and single‐gene etiology

open access: yesEpilepsia, EarlyView.
Abstract Objective To characterize the clinical, electroencephalographic, and genetic features of epilepsies featuring absence seizures within monogenic etiology, highlighting the diagnostic, treatment and prognostic implications. Methods We conducted a retrospective, multicenter study including patients with monogenic epilepsies and ...
Simona Balestrini   +50 more
wiley   +1 more source

GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity

open access: yesCell Reports
Summary: Glucose uptake increases during B cell activation and antibody-secreting cell (ASC) differentiation, but conflicting findings prevent a clear metabolic profile at different stages of B cell activation. Deletion of the glucose transporter type 1 (
Theresa E.H. Bierling   +14 more
doaj   +1 more source

GLUT1 Transmembrane Glucose Pathway [PDF]

open access: yesJournal of Biological Chemistry, 1996
Mohsen Lachaal   +4 more
openaire   +1 more source

Data from High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis

open access: gold, 2023
Daniele Avanzato   +12 more
openalex   +1 more source

Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression

open access: yesThe FEBS Journal, EarlyView.
T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera   +5 more
wiley   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

open access: yesThe FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto   +8 more
wiley   +1 more source

Impact of GLUT1 and Ki-67 expression on early-stage lung adenocarcinoma diagnosed according to a new international multidisciplinary classification

open access: bronze, 2012
Yuho Maki   +12 more
openalex   +2 more sources

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

open access: yesImmunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng   +7 more
wiley   +1 more source

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