Results 161 to 170 of about 31,662 (260)

Targeting the Glucose-Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth. [PDF]

Cancer Res Commun
Mazambani S, Park SH, Choe JH, Nguyen AH, Lee BS, Jeong JY, Lee SY, Kim CH, Park YI, Padilla J, Lee J, Thotala D, Oh TG, Singh PK, Hur H, Hur JK, Kim JW, Kim TH.   +17 more
europepmc   +1 more source

Yak (Bos grunniens) Meat Peptides: Effects on Immunity, Hypoxia Tolerance, and Antioxidant Capacity in Hypotonic Hypoxia Mice

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Yak meat peptides can increase immune cell content, oxygen transport capacity, and antioxidant enzyme activities in hypotonic hypoxic mice. Meanwhile, they can reduce oxidative stress, thus enhancing the immunity, antioxidant capacity, and hypoxia tolerance of these mice. They also upregulate hypoxia‐related genes HIF and EPO.
Gaiming Zhao, Ying Zhang, Ke Wang, Long Xu, Mancai Yin, Xiangying Kong, Chaozhi Zhu   +6 more
wiley   +1 more source

GLUT1-mediated HMGB1 O-GlcNAcylation drives hyperglycemia-Induced neutrophil extracellular trap networks formation via TLR4 signaling and exacerbates fibroblast inflammation. [PDF]

Sci Rep
Sun W, Xu J, Li S, Zhao Y, Fu J, Di L, Han D.   +6 more
europepmc   +1 more source

Studies of renal injury IV: The GLUT1 gene protects renal cells from cyclosporine A toxicity [PDF]

, 2002
Jesus H. Dominguez, Manoocher Soleimani, Thomas D. Batiuk   +2 more
openalex   +1 more source

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

MedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar, Sana Khurshid Baba, Inamu Rashid Khan, Mohd Shahnawaz Khan, Fohad Mabood Husain, Saheem Ahmad, Mohammad Haris, Mayank Singh, Ammira S. Al‐Shabeeb Akil, Muzafar A. Macha, Ajaz A. Bhat   +10 more
wiley   +1 more source

Synovial advanced glycosylation end products aggravate periprosthetic infection in diabetes by upregulating <i>Staphylococcus aureus</i> RNAIII. [PDF]

J Orthop Translat
Dai T, Wen Y, Li Q, Wang H, Liao H, Pu Y, Chen L.   +6 more
europepmc   +1 more source

Minor Effect of GLUT1 Polymorphisms on Susceptibility to Diabetic Nephropathy in Type 1 Diabetes [PDF]

, 2002
Daniel Ng, Luís Henrique Santos Canani, Shin‐ichi Araki, Adam M. Smiles, Dariusz Moczulski, James H. Warram, Andrzej S. Królewski   +6 more
openalex   +1 more source

Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications

MedComm, Volume 6, Issue 7, July 2025.
Macrophage functions in phagocytosis, tissue repair, immune regulation, and neuronal network protection. And graphic abract image in the attachment. ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. This duality underpins their
Yongquan Chi, Haipeng Jiang, Yiyuan Yin, Xinyu Zhou, Yiyouyou Shao, Yongsheng Li, Jianhua Rao   +6 more
wiley   +1 more source

In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment. [PDF]

Nutrients
Rafiei P, Mian HS, Iyer SH, Draves SB, Matthews SA, Rendon DE, Neesen EJ, Dunlay M, Revis M, Glisan AL, Simeone TA, Simeone KA.   +11 more
europepmc   +1 more source

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source