Amyloid beta peptides inhibit glucose transport at the blood-brain barrier by disrupting the insulin-AKT pathway. [PDF]
Wang L+9 more
europepmc +1 more source
Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress [PDF]
Charles M. Heilig+9 more
openalex +1 more source
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song+3 more
wiley +1 more source
Glut1 Deficiency Syndrome: Novel Pathomechanisms, Current Concepts, and Challenges. [PDF]
Klepper J.
europepmc +1 more source
Interactions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose‐binding site of the human erythrocyte glucose transporter GLUT1 [PDF]
Richard J Naftalin+6 more
openalex +1 more source
Immunohistochemistry was used to evaluate the expression of TBC1D1 and tumor microenvironment markers in tumors. By analyzing these indicators, the prognostic value of TBC1D1 and its correlation were explored. In addition, single cell RNA sequencing was used to reveal the expression distribution and proportion of TBC1D1 in different cell populations ...
Linfeng Yang+9 more
wiley +1 more source
Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke. [PDF]
Thieren L+17 more
europepmc +1 more source
Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene [PDF]
Peter Lange+4 more
openalex +1 more source
ABSTRACT Background Markers of cerebral metabolism measured by microdialysis (CMD) may warn clinicians of impending neuroworsening in patients with severe acute brain injury. This retrospective study investigated the relationship between systemic glucose levels and microdialysate glucose (CMD‐glucose) in patients with severe traumatic brain injury (TBI)
Anne‐Sophie Worm Fenger+8 more
wiley +1 more source
Identification of Rapaglutin E as an Isoform-Specific Inhibitor of Glucose Transporter 1. [PDF]
Kotlyar M+8 more
europepmc +1 more source