Results 211 to 220 of about 47,601 (323)

Role and Molecular Mechanisms of Aerobic Glycolysis in Gastrointestinal Tumors. [PDF]

J Cancer
Lei Y, Peng L, Qin Z, Luo J, Luo Y, Fan Z, Wang J, Huang S, Zhao H, Lin S, Xiang L, Luo Y.   +11 more
europepmc   +1 more source

Theranostic Nanoparticles in Prostate Cancer: Disrupting Hypoxia‐Induced Glycolysis by Targeting Hypoxia‐Inducible Factor‐1 Alpha and Downstream Metabolites

Cancer Medicine, Volume 15, Issue 1, January 2026.
The debate in the field of cancer immunotherapy is being changed as nanotechnology breaks the obstacle of cancer immune evasion, target delivery, and systemic toxicity. Esthetically advanced methods that are discussed in this review are nanovaccine, nanoparticle‐enabled checkpoint barrier, cytokine delivery, and T‐cell modulation techniques that ...
Daniel Ejim Uti, Wilson Achu Omang, Esther Ugo Alum, Inalegwu Bawa, Okechukwu Paul‐Chima Ugwu, Ayodeji Oluwafemi Idowu, Item Justin Atangwho, Godwin Eneji Egbung   +7 more
wiley   +1 more source

Metabolic regulation of regulatory T cells: mechanisms, heterogeneity, and implications in disease. [PDF]

Front Immunol
Getachew F, Hu J, Benamar M.
europepmc   +1 more source

Circular RNAs in Diabetic Foot Ulcers: A Scoping Review of Clinical, Preclinical, and In Silico Evidence on Diagnostic and Therapeutic Potentials

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian, Masoomeh Hamdi, Atefeh Soltan Mohseni, Maryam Davoudi, Hamid Choobineh, Fariba Nabatchian, Reza Afrisham   +6 more
wiley   +1 more source

Development and validation of a nomogram comprising GLUT1 and clinical characteristics for predicting overall survival in intrahepatic cholangiocarcinoma. [PDF]

Transl Cancer Res
Gong LP, Weng Y, Zhou J, Huang X, Chen JN, He D, Zhang YW, Cui Y, Liang J, Shao CK.   +9 more
europepmc   +1 more source

Medulla Tetrapanacis Water Extract Ameliorates Dextran Sulfate Sodium‐Induced Ulcerative Colitis by Reprogramming Macrophage Polarization and Maintaining Intestinal Barrier Integrity

Food Frontiers, Volume 7, Issue 1, January 2026.
The protective effects of Medulla Tetrapanacis (MT) water extract on dextran sulfate sodium‐induced ulcerative colitis (UC) were examined both in vivo (mouse and zebrafish) and in vitro. The effect of MT on UC was mediated by regulating macrophage polarization, ameliorating oxidative stress, and preserving an intact intestinal barrier. The effect of MT
Yanfen Cheng, Carsten Tsun‐Ka Kwok, Zi‐Wen Yang, Xi Feng, George Pak‐Heng Leung, Simon Ming‐Yuen Lee, Franklin Wang‐Ngai Chow, Lele Zhang, Daniel Kam‐Wah Mok, Sai‐Wang Seto, Jingjing Li   +10 more
wiley   +1 more source

Vitamin D promotes apoptosis and enhances cisplatin sensitivity in bladder cancer cells by inhibiting the Warburg effect through the AKT/mTOR pathway. [PDF]

BMC Urol
Zhou J, Zhang C, Wang X, Xing J, Cheng G, Chu H.   +5 more
europepmc   +1 more source

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

Glia, Volume 74, Issue 1, January 2026.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli, Insa Hirschberg, Christin Weissleder, Carmela Giachino, María José Pérez, Malvina Dubroux, Francesca Provenzano, Mafalda Rizzuti, Linda Ottoboni, Udit Sheth, Tania F. Gendron, Stefania Corti, Michela Deleidi   +12 more
wiley   +1 more source

Time-dependent biphasic alterations in brain metabolism following chronic ketamine exposure in mice. [PDF]

Front Pharmacol
Lim SH, Choi YS, Kim E, Kim CH, Song HT.
europepmc   +1 more source

Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois   +10 more
wiley   +1 more source