Results 231 to 240 of about 47,601 (323)

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

Association of single nucleotide polymorphisms in the gene encoding GLUT1 and diabetic nephropathy in Brazilian patients with type 1 diabetes mellitus

open access: green, 2015
Tatiana M. Marques   +13 more
openalex   +1 more source

The Effects of Biofortified Cowpeas on Iron, Glucose, and Lipid Metabolism in Rats Fed a High‐Fat/High‐Sugar Diet

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
Biofortified cowpea Aracê improved crypt size in the colon, lowered insulin levels. Biofortified cowpeas increased short‐chain fatty acids. Cowpeas increased HDL‐c concentrations, reduced the total cholesterol/HDL‐c ratio, and decreased fecal triglyceride excretion.
Ana Paula Ribeiro Gaspar   +9 more
wiley   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

open access: yesThe Prostate, Volume 86, Issue 1, Page 65-83, January 2026.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard   +17 more
wiley   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates   +26 more
wiley   +1 more source

GLUT and FAPα as molecular markers for interstitial lung disease in systemic sclerosis. [PDF]

open access: yesRespir Res
Broens B   +10 more
europepmc   +1 more source

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