Results 21 to 30 of about 31,662 (260)

Functional Studies of Threonine 310 Mutations in Glut1 [PDF]

open access: yesJournal of Biological Chemistry, 2003
We have previously reported on a patient with the Glut1 deficiency syndrome (Online Mendelian Inheritance in Man number 606777) carrying a heterozygous T310I missense mutation in the GLUT1 gene (Klepper, J., Wang, D., Fischbarg, J., Vera, J. C., Jarjour, I. T., O'Driscoll, K. R., and De Vivo, D. C. (1999) Neurochem. Res. 24, 587-594).
Kavita M. Swaroop   +10 more
openaire   +3 more sources

GLUT1 and GLUT8 in endometrium and endometrial adenocarcinoma [PDF]

open access: yesModern Pathology, 2006
Glucose is provided to cells by a family of glucose transport facilitators known as GLUTs. These transporters are expressed in a tissue specific manner and are overexpressed in many primary tumors of these tissues. Regulation of glucose transport facilitator expression has been demonstrated in endometrial tissue and endometrial adenocarcinoma.
Noah A. Goldman   +11 more
openaire   +2 more sources

Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice

open access: yesJournal of Neuroinflammation, 2023
Introduction Glucose transporter 1 (GLUT1) is essential for glucose transport into the brain and is predominantly expressed in the cerebral microvasculature.
Ying Chen   +4 more
doaj   +1 more source

Comprehensive Analysis of GLUT1 Immune Infiltrates and ceRNA Network in Human Esophageal Carcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundGlucose transporter 1 (GLUT1) is encoded by the solute carrier family 2A1 (SLC2A1) gene and is one of the glucose transporters with the greatest affinity for glucose. Abnormal expression of GLUT1 is associated with a variety of cancers. However,
Xu-Sheng Liu   +14 more
doaj   +1 more source

The Role of Glucose Transporter 1 in Drug Delivery: Transporter, Receptor and/or Signaling Component

open access: yesNano Biomedicine and Engineering, 2019
The targeting of cell surface molecules is a promising strategy in drug delivery. Glucose modified-nanocarrier interacts with glucose transporter 1 (GLUT1) as a target molecule and increases nanocarrier-drug internalization to cancer and brain ...
Shiva Mehran, Zafar Gholinejad
doaj   +1 more source

Glut1 deficiency syndrome: New and emerging insights into a prototypical brain energy failure disorder

open access: yesNeuroscience Insights, 2021
Considering its small size relative to the rest of the body, the mammalian brain has a disproportionately high energy requirement. This energy is supplied to the brain mainly in the form of glucose through the principal cerebral glucose transporter ...
Maoxue Tang, Umrao R Monani
doaj   +1 more source

Effect of insulin and cinnamon extract on spatial memory and gene expression of GLUT1, 3, and 4 in streptozotocin-induced Alzheimer’s model in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): Since diminished hippocampal insulin signaling leads to memory impairment, insulin resistance and hyperinsulinemia are probably associated with Alzheimer’s disease (AD).
Elham Sajadi   +3 more
doaj   +1 more source

GLUT1 DEFICIENCY AND ALTERNATING HEMIPLEGIA OF CHILDHOOD [PDF]

open access: yesNeurology, 2009
Alternating hemiplegia of childhood (AHC) is a neurodevelopmental syndrome of uncertain etiology.1 It is characterized by onset of hemiplegic, tonic, or dystonic episodes occurring before the age of 18 months. Progressive ataxia and cognitive impairment are frequent.
Hongyuan Yang   +5 more
openaire   +3 more sources

LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis

open access: yesNeuropsychiatric Disease and Treatment, 2021
Lixia Yang, Liangyan Pei, Jilong Yi Department of Neurology, The First People’s Hospital of Jingmen Affiliated to Hubei Minzu University, Jingmen, 434000, People’s Republic of ChinaCorrespondence: Jilong YiDepartment of Neurology, The First ...
Yang L, Pei L, Yi J
doaj  

Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease.

open access: yesPLoS ONE, 2023
Blood-brain barrier (BBB) dysfunction may be involved in the increased sensitivity of Alzheimer's disease (AD) patients to antipsychotics, including amisulpride.
Sevda T Boyanova   +13 more
doaj   +1 more source

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