Results 31 to 40 of about 47,601 (323)
Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family
Life Science Alliance, 2021 A new structure of GLUT1, compared with GLUT3, can explain substrate affinity differences, and provide a functional rationale for key structural motifs that define the universal Sugar Porter family.
T. Custódio +3 more
semanticscholar +1 more source
Understanding the Spectrum of SLC2A1-Associated Disorders
Pediatric Neurology Briefs, 2017 Investigators from the Danish Epilepsy Center the frequency of SLC2A1 mutations in a cohort of patients with different types of epilepsies.
Marytery Fajardo, Melissa L. Cirillo
doaj +1 more source
Epilepsia Open, 2020 Glut1 deficiency syndrome (Glut1DS) is a brain energy failure syndrome caused by impaired glucose transport across brain tissue barriers. Glucose diffusion across tissue barriers is facilitated by a family of proteins including glucose transporter type 1
J. Klepper +23 more
semanticscholar +1 more source
The Lancet Infectious Diseases, 2016 We read with interest the Grand Round by Nicole Salazar-Austin and colleagues, who reported a young child with extensively drug-resistant tuberculosis after returning from India to the USA. Recently, we admitted a previously healthy man aged 20 years to our hospital in Germany who developed fever and productive cough 3 months after returning from ...
openaire +2 more sources
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2021 Emerging evidence has demonstrated that N6‐methyladenosine (m6A) and long noncoding RNAs (lncRNAs) are both crucial regulators in gastric cancer (GC) tumorigenesis. However, the interaction of m6A and lncRNAs in GC progression are still unclear.
De-sheng Yang +7 more
semanticscholar +1 more source
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Endothelial cells (ECs) are highly glycolytic and generate the majority of their energy via the breakdown of glucose to lactate.
K. Veys +26 more
semanticscholar +1 more source
GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration
Scientific Reports, 2021 The mammalian heart switches its main metabolic substrate from glucose to fatty acids shortly after birth. This metabolic switch coincides with the loss of regenerative capacity in the heart.
Viviana M. Fajardo +11 more
semanticscholar +1 more source
TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A
Scientific Reports, 2021 TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remission after the
Kathrin Koedderitzsch +4 more
semanticscholar +1 more source
Frontiers in Oncology, 2022 Increased glycolysis in tumor cells is frequently associated with drug resistance. Overexpression of glucose transporter-1 (GLUT1) promotes the Warburg effect and mediates chemoresistance in various cancers.
Peixin Dong +8 more
semanticscholar +1 more source
Journal of Cancer, 2022 Pancreatic adenocarcinoma (PAAD) is a digestive tumor with extremely high malignancy. Previous studies have reported that Glucose transporter 1 (GLUT1) contributes to the aggressive tumor progression in various cancer types and indicates an unfavorable ...
F. Li +14 more
semanticscholar +1 more source