Results 31 to 40 of about 31,662 (260)
Біологічні студії, 2009 Expression of vascular endothelial growth factor (VEGF), glucose transporter Glut1 and two members of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase family (PFKFB-3 and PFKFB-4) in lung, colon and gastric cancers was studied.
D. O. Minchenko +8 more
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GLUT1 Expression in Cutaneous Sebaceous Lesions Determined by Immunohistochemical Staining Patterns
Dermatopathology, 2021 GLUT1 is a membrane associated carrier protein that functions in the physiologic transport of glucose across cell membranes. Multiple studies have shown an increased GLUT1 expression in various tumor types and a role in cancer prognosis.
Cynthia Reyes Barron, Bruce R. Smoller
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A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome [PDF]
Molecular Cell, 2015 Protein kinase C has been implicated in the phosphorylation of the erythrocyte/brain glucose transporter, GLUT1, without a clear understanding of the site(s) of phosphorylation and the possible effects on glucose transport. Through in vitro kinase assays, mass spectrometry, and phosphospecific antibodies, we identify serine 226 in GLUT1 as a PKC ...
Eunice E. Lee +11 more
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Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
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Biomolecules, 2023 This study investigated the critical role of Glut1-mediated glucose metabolism in the inflammatory response of macrophages, which are energy-intensive cells within the innate immune system.
Alex Cornwell +2 more
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Oncoprotein LAMTOR5 activates GLUT1 via upregulating NF-κB in liver cancer
Open Medicine, 2019 Accumulating reports reveal that serving as an oncogenic factor LAMTOR5 is involved in the progression of many specific cancers. Glucose transporter 1 (GLUT1) is frequently identified in many cancers.
Zhou Jing +4 more
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Prolactin-induced Subcellular Targeting of GLUT1 Glucose Transporter in Living Mammary Epithelial Cells [PDF]
Rambam Maimonides Medical Journal, 2015 Background: Studying the biological pathways involved in mammalian milk production during lactation could have many clinical implications. The mammary gland is unique in its requirement for transport of free glucose into the cell for the synthesis of ...
Arieh Riskin, Yehudit Mond
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The Effects of GLUT1 on the Survival of Head and Neck Squamous Cell Carcinoma
Cellular Physiology and Biochemistry, 2013 Background/Aims: Cancer cells require increased nutrient uptake to support a high rate of proliferation, and the overexpression of glucose transporters, in particular GLUT1, is a common characteristic of human malignancies.
Shengjiao Li +3 more
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An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking [PDF]
Biochemical Journal, 2009 Cell surface localization of the Glut (glucose transporter), Glut1, is a cytokine-controlled process essential to support the metabolism and survival of haemopoietic cells. Molecular mechanisms that regulate Glut1 trafficking, however, are not certain.
Sally Kornbluth +5 more
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Drug Design, Development and Therapy, 2020 Peng Gao,1,2 Shuo Shen,1,2 Xiaodong Li,3 Dandan Liu,1,2 Yuqing Meng,1,2 Yanqing Liu,1,2 Yongping Zhu,1,2 Junzhe Zhang,1,2 Piao Luo,1,2 Liwei Gu1,2 1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, People ...
Gao P +9 more
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