Results 51 to 60 of about 47,601 (323)

Deletion of Glut1 in early postnatal cartilage reprograms chondrocytes toward enhanced glutamine oxidation

Bone Research, 2021
Glucose metabolism is fundamental for the functions of all tissues, including cartilage. Despite the emerging evidence related to glucose metabolism in the regulation of prenatal cartilage development, little is known about the role of glucose metabolism
Cuicui Wang, J. Ying, Xiangfeng Niu, Xiaofei Li, G. Patti, Jie Shen, R. O’Keefe   +6 more
semanticscholar   +1 more source

Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice

Journal of Neuroinflammation, 2023
Introduction Glucose transporter 1 (GLUT1) is essential for glucose transport into the brain and is predominantly expressed in the cerebral microvasculature.
Ying Chen, Jin Joo, John Man-Tak Chu, Raymond Chuen-Chung Chang, Gordon Tin-Chun Wong   +4 more
doaj   +1 more source

Prognostic value of glucose transporter proteins-1 (GLUT1) in breast carcinoma

Libyan Journal of Medicine, 2023
Several studies have reported increased glucose transporters (GLUT) expression in different cancer types, including breast cancer. The primary purpose of this study is to examine GLUT1 immunoexpression in breast cancer patients in Saudi Arabia and to ...
Mehenaz Hanbazazh, Abdulhadi Samman, Saad Samargandy, Jaudah Al-Maghrabi   +3 more
doaj   +1 more source

Paroxysmal Nonepileptic Events in Glut1 Deficiency [PDF]

Movement Disorders Clinical Practice, 2016
AbstractView Supplementary Video 1View Supplementary Video 2View Supplementary Video 3Movement disorders are a major feature of Glut1 deficiency. As recently identified in adults with paroxysmal exercise‐induced dystonia, similar events were reported in pediatric Glut1 deficiency.
Klepper, Jörg, Leiendecker, Baerbel, Eltze, Christin, Heussinger, Nicole   +3 more
openaire   +3 more sources

Icaritin-Induced FAM99A Affects GLUT1-Mediated Glycolysis via Regulating the JAK2/STAT3 Pathway in Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Icaritin is a potential treatment option for hepatocellular carcinoma (HCC) based on the results of its phase 2 stage trial. Glucose transporter 1 (GLUT1), a critical gene in regulating glycolysis, has been recognized as a promising target in HCC ...
Xia Zheng, Yu-Jing Gou, Ziyu Jiang, Aizhen Yang, ZhiHui Yang, S. Qin   +5 more
semanticscholar   +1 more source

GLUT1 exacerbates trophoblast ferroptosis by modulating AMPK/ACC mediated lipid metabolism and promotes gestational diabetes mellitus associated fetal growth restriction

Molecular Medicine
Gestational diabetes mellitus (GDM) has been associated with several fetal complications, such as macrosomia and fetal growth restriction (FGR). Infants from GDM associated FGR are at increased risk for adult-onset obesity and associated metabolic ...
Qin Zhang, Xi Yuan, Xiaojin Luan, Ting Lei, Yiran Li, Wei Chu, Qiong Yao, Philip N. Baker, Hongbo Qi, Hui Li   +9 more
semanticscholar   +1 more source

Prolactin-induced Subcellular Targeting of GLUT1 Glucose Transporter in Living Mammary Epithelial Cells [PDF]

Rambam Maimonides Medical Journal, 2015
Background: Studying the biological pathways involved in mammalian milk production during lactation could have many clinical implications. The mammary gland is unique in its requirement for transport of free glucose into the cell for the synthesis of ...
Arieh Riskin, Yehudit Mond
doaj   +1 more source

De Vivo disease (myoclonic-astatic epilepsy combined with chorea): literature review, clinical case description

Эпилепсия и пароксизмальные состояния
De Vivo disease is a rare genetic disorder associated with glucose transporter type 1 (GLUT1) deficiency. We provide a review of publications describing various clinical manifestations of this syndrome, including the combination of epilepsy with choreic ...
N. I. Shova, V. A. Mikhailov, G. D. Romanyugo   +2 more
doaj   +1 more source

The Effects of GLUT1 on the Survival of Head and Neck Squamous Cell Carcinoma

Cellular Physiology and Biochemistry, 2013
Background/Aims: Cancer cells require increased nutrient uptake to support a high rate of proliferation, and the overexpression of glucose transporters, in particular GLUT1, is a common characteristic of human malignancies.
Shengjiao Li, Xiaoning Yang, Peng Wang, Xing Ran   +3 more
doaj   +1 more source

Tumor cell membrane-coated continuous electrochemical sensor for GLUT1 inhibitor screening

Journal of Pharmaceutical Analysis, 2023
Glucose transporter 1 (GLUT1) overexpression in tumor cells is a potential target for drug therapy, but few studies have reported screening GLUT1 inhibitors from natural or synthetic compounds.
Jiaqian Zhao, Yuqiao Liu, Ling Zhu, Junmin Li, Yanhui Liu, Jiarui Luo, Tian Xie, Dajing Chen   +7 more
doaj   +1 more source