Results 51 to 60 of about 31,662 (260)
Эпилепсия и пароксизмальные состоянияDe Vivo disease is a rare genetic disorder associated with glucose transporter type 1 (GLUT1) deficiency. We provide a review of publications describing various clinical manifestations of this syndrome, including the combination of epilepsy with choreic ...
N. I. Shova +2 more
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Frontiers in Bioscience-Landmark, 2023 Background: Macrophages expressing CC chemokine receptor 2 (CCR2) possess characteristics and performance akin to M1 polarized macrophages, which promote inflammation.
Chao Feng +5 more
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Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
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Glucose Transporter-1 Cooperating with AKT Signaling Promote Gastric Cancer Progression
Cancer Management and Research, 2020 Diyuan Zhou,1,* Linhua Jiang,1,* Lichen Jin,1,* Yizhou Yao,1 Peijie Wang,2 Xinguo Zhu1 1Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Institute of Mental Health ...
Zhou D +5 more
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An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression
Scientific Reports, 2023 Glucose, a primary fuel source under homeostatic conditions, is transported into cells by membrane transporters such as glucose transporter 1 (GLUT1).
Yajuan Shi +7 more
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GLUT1 and TUBB4 in Glioblastoma Could be Efficacious Targets [PDF]
Cancers, 2019 Glioblastoma multiforme (GBM) is the most aggressive and deadly brain tumor, portending a median 13-month survival even following gross total resection with adjuvant chemotherapy and radiotherapy. This prognosis necessitates improved therapies for the disease.
Maheedhara R. Guda +7 more
openaire +3 more sources
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2023 Background/Aims: Glucose metabolism has been proven as an essential process for proliferating keratinocytes, which highlights the importance of glucose transporter-1 (GLUT1) not only in the onset of psoriasis but also in the progression and severity of ...
Sebastian Makuch
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Advanced Therapeutics, EarlyView.This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen +2 more
wiley +1 more source
Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis
Cancer Management and Research, 2020 Xiaoping Li,1 Jie Sun,2 Qinghua Xu,1 Weiping Duan,2 Licheng Yang,1 Xing Wu,1 Guang Lu,1 Li Zhang,1 Yunfeng Zheng2 1Department of General Surgery, Liyang People′s Hospital, Jiangsu 213300, People’s Republic of China; 2School of Pharmacy ...
Li X +8 more
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