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High expression of glutamate‐ammonia ligase is associated with unfavorable prognosis in patients with ovarian cancer

Journal of Cellular Biochemistry, 2018
AbstractGlutamate‐ammonia ligase (GLUL), which is also called GS (glutamine synthetase), is the enzyme that catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP‐dependent reaction. Here, we found higher expression of GLUL in the ovarian cancer patients was associated with worse disease‐free survival (DFS) and overall survival (OS).
Shaohua Fan, Zifeng Zhang, Jun Lu
exaly   +3 more sources

Glutamate‐ammonia ligase and reduction of G0 population in PANC‐1 cells

Journal of Cellular Biochemistry, 2012
AbstractIn our previous study, we screened and isolated genes that were up‐regulated after partial pancreatectomy using transcriptomic analysis and glutamate‐ammonia ligase (GLUL) was selected for further study based on its effect on differentiation and proliferation. In the immunohistochemical analysis, GLUL was highly up‐regulated in the acinar cells
Jong-Ho, Choi   +5 more
openaire   +2 more sources

Hsa_circ_0007349 upregulates glutamate-ammonia ligase to modulate gingival fibroblast wound healing

Archives of Oral Biology
Human gingival fibroblasts (HGFs) are important cells that maintain the structure and integrity of periodontal tissues. Circular RNAs (circRNAs) play critical roles in cellular processes of periodontitis; however, their roles in HGFs remain unclear.
Liang Ren   +7 more
openaire   +2 more sources

Novel Glutamate–Putrescine Ligase Activity in Haloferax mediterranei: A New Function for glnA-2 Gene

Biomolecules, 2021
Mónica Camacho   +2 more
exaly  

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