Results 171 to 180 of about 585,844 (339)

20-hydroxyecdysone promotes brain development via upregulating MMP2 expression during metamorphosis in Helicoverpa armigera. [PDF]

PLoS Genet
Tian C, Feng PY, Wang L, Liu TW, Li YX, Zhao XF.   +5 more
europepmc   +1 more source

Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders

Neuropsychopharmacology, 2017
E. Haroon, Andrew H. Miller, G. Sanacora
semanticscholar   +1 more source

Large‐scale case‐control study of a functional polymorphism in the glutamate receptor, metabotropic 3 gene in patients with schizophrenia [PDF]

, 2008
Ayako Nunokawa, Yuichiro Watanabe, Hideaki Kitamura, Naoshi Kaneko, Tadao Arinami, Hiroshi Ujike, Toshiya Inada, Nakao Iwata, Hiroshi Kunugi, Masanari Itokawa, Norio Ozaki, Toshiyuki Someya   +11 more
openalex   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

Advanced Science, EarlyView.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang, Yida Liu, Zhi Zhang, Yang Wang, Fusheng Liu   +4 more
wiley   +1 more source

Bromelain Restores Glutamatergic Homeostasis via Regulation of NR2A, GLT-1, EAAC1, and xCT in Arsenic-Induced Cerebral Cortex and Hippocampal Neurotoxicity. [PDF]

F1000Res
Emeka Godson A, Chinua Ogonnadi K, Uchenna Agu A, Johnson Nto N, Aniaku I, Yvonne Nwabueze Y, Onyinye Ojiakor V, Chinyere Nkemjika A.   +7 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Correction: Association of glutamine metabolites in synovial fluid with the severity of temporomandibular joint osteoarthritis. [PDF]

BMC Musculoskelet Disord
Song Z, Xu Y, Li C, Shao B, Gong Z.
europepmc   +1 more source

Role of Glutamate and NMDA Receptors in Alzheimer’s Disease

Journal of Alzheimer's Disease, 2016
Rui Wang, P. Reddy
semanticscholar   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Exploring the Neuroprotective Properties of Capsanthin: Antioxidant Defense and Inflammatory Responses. [PDF]

Nutrients
Pap R, Pandur E, Jánosa G, Horváth A, Tamási K, Sipos K, Agócs A, Deli J.   +7 more
europepmc   +1 more source