Results 201 to 210 of about 585,844 (339)

Modular Model of Neuronal Activity That Captures the Dynamics of Main Molecular Targets of Antiepileptic Drugs. [PDF]

Int J Mol Sci
Kondrakhin PY, Kolpakov FA.
europepmc   +1 more source

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

Nature Reviews Neuroscience, 2011
M. Popoli, Zhen Yan, B. McEwen, G. Sanacora   +3 more
semanticscholar   +1 more source

Neuroprotective Effect of β-Lapachone against Glutamate-Induced Injury in HT22 Cells

Hyun Sook Lee, Hye Jin Jee, Yi-Sook Jung
openalex   +2 more sources

Mapping Charge Interactions in Intrinsically Disordered Proteins

Advanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips, Andrea Holla, Magdalena Wojtas, Aritra Chowdhury, Andrea Sottini, Sebastian L. B. König, Natalie Mutter, Nick Lamb, Jonathan Huihui, Monika Lopko, Andrea Soranno, Daniel Nettels, Andrzej Ożyhar, Benjamin Schuler, Kingshuk Ghosh   +14 more
wiley   +1 more source

Could Glutamine Feed Epileptogenesis? [PDF]

Epilepsy Curr
Borges K.
europepmc   +1 more source

Localization of neuronal and glial glutamate transporters

Neuron, 1994
J. Rothstein, L. Martin, A. Levey, M. Dykes‐Hoberg, Lin Jin, David Wu, N. Nash, R. Kuncl   +7 more
semanticscholar   +1 more source

Genetic Pathways Regulating Glutamate Levels in Retinal Müller Cells

, 2010
Monica M. Jablonski, Natalie E. Freeman, William E. Orr, Justin P. Templeton, Lu Lu, Robert W. Williams, Eldon E. Geisert   +6 more
openalex   +2 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Glutamate as a neurotransmitter in the brain: review of physiology and pathology.

Journal of NutriLife, 2000
B. Meldrum
semanticscholar   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source