Results 251 to 260 of about 732,660 (295)

Synaptic Pathology in Traumatic Brain Injury and Therapeutic Insights. [PDF]

Int J Mol Sci
Nuthalapati P, Holmes SE, Altalib HH, Fesharaki-Zadeh A.   +3 more
europepmc   +1 more source

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source

Multifaceted disruption of AMPA receptor signaling by <i>CACNG8</i> variants: Integrated evidence from human genetics and molecular simulation. [PDF]

Comput Struct Biotechnol J
Alibrandi S, Mordà D, Scimone C, Abate G, Chust IB, Rinaldi C, Poggi L, Scalinci SZ, D'Angelo R, Sidoti A, Donato L.   +10 more
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Detecting MUNC18-1 related presynaptic dysfunction and rescue in human iPSC-derived neurons. [PDF]

Sci Rep
Long M, Gallo NB, Zoll J, Unnikrishnan S, Guilmette E, Gianni D, Wu S, Hinckley CA.   +7 more
europepmc   +1 more source

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

Advanced NanoBiomed Research, EarlyView.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane, Heidi Abrahamse   +1 more
wiley   +1 more source

An Emerging Paradigm for ABCC5/MRP5 Function in Human Physiology. [PDF]

Int J Mol Sci
Chinoy J, Meller C, de Wet H.
europepmc   +1 more source

Neuroprotective effects of an extract from the inflamed skin of rabbits inoculated with vaccinia virus on glutamate-induced neurotoxicity in cultured neuronal cell line

, 2008
Tatsuki Itoh, Takao Satou, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Hiroyuki Ito   +5 more
openalex   +2 more sources

Impact of Interfacial Viscosity on the Robustness of Phospholipid‐Decorated Fluid Cell Scaffolds

Advanced NanoBiomed Research, EarlyView.
Viscosity‐tunable fluid scaffolds are developed by decorating a perfluorocarbon interface with phospholipid membranes (IPLMs) of varying unsaturated lipid contents. A solid‐like IPLM is cell‐adhesive but brittle, whereas the least viscous IPLM does not allow cell adhesion. Moderately viscous IPLMs serve as highly adaptive cellular scaffolds.
Junhong Zhou, Jun Nakanishi
wiley   +1 more source

Impact of climate change driven freshening, warming, and ocean acidification on the cellular metabolism of Atlantic Cod (Gadus morhua). [PDF]

Sci Rep
Thor P, Perry D.
europepmc   +1 more source