Results 101 to 110 of about 13,611 (195)

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis. [PDF]

Sci Transl Med, 2023
Peters DE, Norris LD, Tenora L, Šnajdr I, Ponti AK, Zhu X, Sakamoto S, Veeravalli V, Pradhan M, Alt J, Thomas AG, Majer P, Rais R, McDonald C, Slusher BS.   +14 more
europepmc   +1 more source

In-silico study of thiazolidinone-linked Glu-Ureido based PSMA ligands for PET application

Discover Chemistry
Introduction The Prostate Specific Membrane Antigen (PSMA) is a type II transmembrane glycoprotein known as Glutamate Carboxypeptidase II, overexpressed in prostate carcinoma.
Mohd. Faheem, Vaibhav Pandey, Manisha Prasad, Manish Dixit   +3 more
doaj   +1 more source

Characterization of the Catalytically Active Mn(II)-loaded \u3cem\u3eargE\u3c/em\u3e-encoded \u3cem\u3eN\u3c/em\u3e-acetyl-L-ornithine Deacetylase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2007
The catalytically competent Mn(II)-loaded form of the argE-encoded N-acetyl-l-ornithine deacetylase from Escherichia coli (ArgE) was characterized by kinetic, thermodynamic, and spectroscopic methods.
Bennett, Brian, Holz, Richard C., McGregor, Wade C., Swierczek, Sabina I.   +3 more
core   +1 more source

A comparative assessment of radiochemical purity and yield of [18F]PSMA-1007 production using two different automated synthesis platforms: a head-to-head comparison

EJNMMI Radiopharmacy and Chemistry
Background Glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA) is overexpressed in 90–100% of prostate cancer cells. The radiopharmaceutical [18F]PSMA-1007, recognised as a PET tracer for prostate cancer imaging,
Michela Cossandi, Massimo Statuto, Elena Migliorati, Gian Luca Viganò, Luigi Spiazzi, Carlo Rodella, Pietro Bellini, Roberto Rinaldi, Luca Camoni, Francesco Dondi, Giorgio Biasiotto, Francesco Bertagna   +11 more
doaj   +1 more source

Combination of <i>In Silico</i> and <i>In Vitro</i> Screening to Identify Novel Glutamate Carboxypeptidase II Inhibitors. [PDF]

J Chem Inf Model, 2023
Temml V, Kollár J, Schönleitner T, Höll A, Schuster D, Kutil Z.   +5 more
europepmc   +1 more source

A large-scale analysis of mRNAs expressed by primary mesenchyme cells of the sea urchin embryo [PDF]

, 2001
The primary mesenchyme cells (PMCs) of the sea urchin embryo have been an important model system for the analysis of cell behavior during gastrulation.
Cameron, R. Andrew, Davidson, Eric H., Ettensohn, Charles A., llies, Michele, Maharias, Gregory, Zhu, Xiaodong   +5 more
core  

Troriluzole inhibits methamphetamine place preference in rats and normalizes methamphetamine-evoked glutamate carboxypeptidase II (GCPII) protein levels in the mesolimbic pathway. [PDF]

Drug Alcohol Depend, 2023
Wiah S, Roper A, Zhao P, Shekarabi A, Watson MN, Farkas DJ, Potula R, Reitz AB, Rawls SM.   +8 more
europepmc   +1 more source

Senescence and protein degradation in leaf segments of young winter wheat: influence of leaf age [PDF]

, 2017
Leaf senescence in intact wheat plants can be strongly influenced by altered source/sink relations. Interactions with other plant parts are no longer possible in detached leaves and therefore differences in their senescence behaviour reflect the ...
Feller, Urs, Fischer, Andreas
core  

Inhibition of glutamate-carboxypeptidase-II in dorsolateral prefrontal cortex: potential therapeutic target for neuroinflammatory cognitive disorders. [PDF]

Mol Psychiatry, 2022
Yang S, Datta D, Elizabeth Woo, Duque A, Morozov YM, Arellano J, Slusher BS, Wang M, Arnsten AFT.   +8 more
europepmc   +1 more source

\u3cem\u3eargE\u3c/em\u3e-Encoded \u3cem\u3eN\u3c/em\u3e-Acetyl-l-Ornithine Deacetylase from \u3cem\u3eEscherichia coli\u3c/em\u3e Contains a Dinuclear Metalloactive Site [PDF]

, 2005
The catalytic and structural properties of the argE-encoded N-acetyl-l-ornithine deacetylase (ArgE) from Escherichia coli were investigated. On the basis of kinetic and ITC (isothermal titration calorimetry) data, Zn(II) binds to ArgE with Kd values that
Bennett, Brian, Holz, Richard C., McGregor, Wade C., Swierczek, Sabina I.   +3 more
core   +1 more source