Results 211 to 220 of about 158,395 (286)

Allosteric regulation of glutamate dehydrogenase deamination activity. [PDF]

open access: yesSci Rep, 2020
Bera S   +7 more
europepmc   +1 more source

Evolution of lysine and arginine biosynthesis revealed by substrate specificity of lysine biosynthetic enzymes in Thermus thermophilus

open access: yesThe FEBS Journal, EarlyView.
Two enzymes from the Thermus thermophilus lysine biosynthetic pathway, LysZ and LysY, unexpectedly exhibit substrate promiscuity. They are able to recognize the LysW intermediates utilized by the ArgW‐mediated arginine route, even though the bacterium already possesses the canonical arginine biosynthetic pathway.
Wenyuan Shi   +3 more
wiley   +1 more source

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

open access: yesThe FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan   +8 more
wiley   +1 more source

Hypoadrenocorticism‐like syndrome in a cat with Tritrichomonas foetus infection: a case report

open access: yesJournal of Small Animal Practice, EarlyView.
A reduced sodium: potassium ratio is an uncommon finding in cats, and is typically associated with conditions such as hypoadrenocorticism, severe renal and cardiovascular diseases, cavitary effusion and certain non‐parasitic gastrointestinal diseases.
M. Crisonà   +4 more
wiley   +1 more source

Discrete and cell‐specific hypoxic responses in Arabidopsis roots resolved by single‐nuclei transcriptomics

open access: yesNew Phytologist, EarlyView.
Summary With the intensification of unpredictable flooding events because of global warming, there is a need to understand how root cells perceive and respond to oxygen deprivation. The use of high‐throughput single‐nuclei RNA‐sequencing (snRNA‐Seq) allows the examination of gene expression profiles in discrete cell types.
Robert D. Hill   +5 more
wiley   +1 more source

Biological characteristics and functions of a novel glutamate dehydrogenase from Trichinella spiralis. [PDF]

open access: yesParasite
Cheng YK   +9 more
europepmc   +1 more source

B‐GATA factors are required for nitrogen‐responsive growth in Physcomitrium patens and Arabidopsis thaliana

open access: yesNew Phytologist, EarlyView.
Summary We hypothesized that B‐GATA family transcription factors have important roles in growth regulation in moss. We analyzed B‐GATA family transcription factor mutants from Physcomitrium patens and Arabidopsis thaliana to assess growth, gene expression, and cytokinin‐related processes under varying nitrogen conditions.
Dario Zappone   +7 more
wiley   +1 more source

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