Results 241 to 250 of about 574,846 (354)

Glutamate Dehydrogenase Is Highly Conserved among Clostridium difficile Ribotypes

open access: yesJournal of Clinical Microbiology, 2012
R. Carman   +7 more
semanticscholar   +1 more source

Tumor‐related epilepsy in glioma: A multidisciplinary overview

open access: yesEpilepsia, EarlyView.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci   +29 more
wiley   +1 more source

Physiological Role of Glutamate Dehydrogenase in Cancer Cells. [PDF]

open access: yesFront Oncol, 2020
Moreno-Sánchez R   +7 more
europepmc   +1 more source

The structure and allosteric regulation of mammalian glutamate dehydrogenase.

open access: yesArchives of Biochemistry and Biophysics, 2012
Ming Li   +4 more
semanticscholar   +1 more source

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen   +25 more
wiley   +1 more source

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

open access: yesEpilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

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