Results 21 to 30 of about 142,175 (352)

Multiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological Implications

Biology, 2016
Glutamate dehydrogenase (GDH) of animal cells is usually considered to be a mitochondrial enzyme. However, this enzyme has recently been reported to be also present in nucleus, endoplasmic reticulum and lysosomes.
Victoria Bunik, Artem Artiukhov, Vasily Aleshin, Garik Mkrtchyan   +3 more
doaj   +1 more source

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development [PDF]

, 2011
<p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized.
Aparicio, I., Engel, P.C., Llinas, M., Muller, S., Olszewski, K., Patzewitz, E.-M., Perner, J., Storm, J.   +7 more
core   +4 more sources

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations [PDF]

, 2009
Background: Activating mutations in the GLUD1 gene (which encodes for the intra-mitochondrial enzyme glutamate dehydrogenase, GDH) cause the hyperinsulinism–hyperammonaemia (HI/HA) syndrome.
Banerjee, I., Ben-Omran, T., Chadefaux, B., Chakrapani, A., Ellard, S., Flanagan, S. E, Fulton, P., Hussain, K., Kapoor, R. R, Shield, J. P   +9 more
core   +2 more sources

Latent acetylcholinesterase in secretory vesicles isolated from adrenal medulla [PDF]

, 1981
A new procedure is described for the preparation of highly purified and stable secretory vesicles from adrenal medulla. Two forms of acetylcholinesterase, a membrane bound form as well as a soluble form, were found within these vesicles.
Abbs, Anton, Bergmeyer, Blakeborough, Carty, Casey, Chubb, Chubb, Creutz, Dahl, Ekerdt, Ellman, Famborough, Farquar, Gratzl, Gratzl, Gratzl, Ingebretsen, Johnson, Laemmli, Lagercrantz, Leighton, Little, Lowry, Lowry, Meyer, Morris, Morris, Omaye, Palade, Rotundo, Rotundo, Schmidt, Smilowitz, Somogyi, Terland, Terland, Trifaro, Winkler   +38 more
core   +1 more source

Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection [PDF]

, 2008
Many new gene copies emerged by gene duplication in hominoids, but little is known with respect to their functional evolution. Glutamate dehydrogenase (GLUD) is an enzyme central to the glutamate and energy metabolism of the cell.
A Courseaux, A Marques, A Plaitakis, A Plaitakis, A Reymond, AC Marques, AC Marques, Ana C. Marques, Andreas S. Reichert, BJ Soltys, CA Paulding, EL Smith, F Burki, H Yu, Henrik Kaessmann, I Small, IE Scheffler, J Brosius, J Zhang, K Kanavouras, KH Berger, L Rosso, L Rosso, Lia Rosso, M Goodman, M Long, M Lynch, ME Johnson, Molly Przeworski, N Pfanner, P Shashidharan, RV Samonte, SA Byun-McKay, TR Schmidt, V Mastorodemos, W Murphy, W Neupert, W-H Li, Z Yang, Z Yang, Z Yang   +40 more
core   +3 more sources

Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes

Frontiers in Endocrinology, 2013
We recently found evidence for anatomic and physical linkages between the astroglial Na+-dependent glutamate transporters (GLT-1/EAAT2 and GLAST/EAAT1) and mitochondria.
Brendan S Whitelaw, Michael B Robinson, Michael B Robinson, Michael B Robinson   +3 more
doaj   +1 more source

Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. [PDF]

, 2011
Label-free LC-MS/MS-based shot-gun proteomics was used to quantify the differential protein synthesis and metabolite profiling in order to assess metabolic changes during the development of citrus fruits.
Blumwald, Eduardo, Boo, Kyung Hwan, Eigenheer, Richard A, Katz, Ehud, Kim, Ho Youn, Negre-Zakharov, Florence, Phinney, Brett S, Sadka, Avi, Shulaev, Vladimir   +8 more
core   +3 more sources

Medium‐chain Acyl‐COA dehydrogenase deficiency: Pathogenesis, diagnosis, and treatment

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
MCADD is a commonly inherited metabolic disease with serious implications for health outcomes, particularly in children, that may be successfully managed with proper intervention. In this review, we discuss the genetics, pathogenesis, clinical presentation, diagnosis, and treatments for Medium‐Chain Acyl‐CoA Dehydrogenase Deficiency (MCADD ...
Emily Mason, Charles C. T. Hindmarch, Kimberly J. Dunham‐Snary   +2 more
wiley   +1 more source

Sodium butyrate reduces ammonia emissions through glutamate metabolic pathways in cecal microorganisms of laying hens

Ecotoxicology and Environmental Safety, 2022
Ammonia emission is an important problem that needs to be solved in laying hen industries. Sodium butyrate (SB) is considered to have potential for reducing ammonia production because of its ability to improve nitrogen metabolism.
Zhikang Zhong, Chao Wang, Huaidan Zhang, Jiandui Mi, Juan Boo Liang, Xindi Liao, Yinbao Wu, Yan Wang   +7 more
doaj  

Metabolism of excised embryos of Lupinus luteus L. VI. An electrophoretic analysis of some dehydrogenases in cultured embryos as compared with the normal seedling axes

Acta Societatis Botanicorum Poloniae, 2015
The electrophoretic patterns (disc electrophoresis) of the studied dehydrogenases: glucose-6-phosphate - (A), malate - (B), glutamate - (C), alcohol - (D) and lactate dehydrogenase (E), in the axial organs of isolated Lupinus luteus embryos and seedlings
J. Czosnowski
doaj   +1 more source