Results 51 to 60 of about 157,588 (333)

METABOLIC PLATELET STATUS IN PATIENTS WITH STABLE ANGINA

Российский кардиологический журнал, 2013
Aim. To study the activity of NAD- and NADP-dependent platelet dehydrogenases in patients with various functional classes of angina. Material and methods. The study included 91 men with Functional Class II–IV angina, aged 45–72 years. In all participants,
I. Yu. Grinstein, A. A. Savchenko, E. A. Savchenko, A. A. Kosinova, Yu. I. Grinstein   +4 more
doaj   +1 more source

Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain

Biomolecules, 2016
Glutamate is present in the brain at an average concentration—typically 10–12 mM—far in excess of those of other amino acids. In glutamate-containing vesicles in the brain, the concentration of glutamate may even exceed 100 mM. Yet because glutamate is a
Arthur J. L. Cooper, Thomas M. Jeitner
doaj   +1 more source

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia, Giulivi, Cecilia, Napoli, Eleonora   +2 more
core   +1 more source

The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots

Acta Societatis Botanicorum Poloniae, 2014
The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus, Genowefa Kłobus-Dobosz, Józef Buczek   +2 more
doaj   +1 more source

The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG. [PDF]

PLoS ONE, 2013
Recent evidence suggests that the regulation of intracellular glutamate levels could play an important role in the ability of pathogenic slow-growing mycobacteria to grow in vivo.
Albertus J Viljoen, Catriona J Kirsten, Bienyameen Baker, Paul D van Helden, Ian J F Wiid   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Molecular and Genetic Determinants of Glioma Cell Invasion. [PDF]

, 2017
A diffusely invasive nature is a major obstacle in treating a malignant brain tumor, "diffuse glioma", which prevents neurooncologists from surgically removing the tumor cells even in combination with chemotherapy and radiation.
Kato, Yoichiro, Masui, Kenta, Mischel, Paul S, Sawada, Tatsuo, Shibata, Noriyuki   +4 more
core   +2 more sources

Geographic and climatic differentiation of electrophoretic forms of esterase, glutamate dehydrogenase and peroxidase in Scots pine tissues

Acta Societatis Botanicorum Poloniae, 2014
The enzymatic systems have been investigated in individual trees derived from 17 distant localities in Europe and Asia. Esterase and glutamate dehydrogenase polymorphism was determined in extracts from mixture of 50 macrogametophytes, iperoxidase ...
Barbara Kieliszewska-Rokicka
doaj   +1 more source

Ketogenic diet in action: Metabolic profiling of pyruvate dehydrogenase deficiency

Molecular Genetics and Metabolism Reports, 2023
The pyruvate dehydrogenase complex serves as the main connection between cytosolic glycolysis and the tricarboxylic acid cycle within mitochondria. An infant with pyruvate dehydrogenase complex deficiency was treated with vitamin B1 supplementation and a
Eri Ogawa, Takako Hishiki, Noriyo Hayakawa, Hisato Suzuki, Kenjiro Kosaki, Makoto Suematsu, Toshiki Takenouchi   +6 more
doaj   +1 more source