Results 51 to 60 of about 4,838 (142)

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

Cell Reports, 2015
Glucose, the main energy substrate used in the CNS, is continuously supplied by the periphery. Glutamate, the major excitatory neurotransmitter, is foreseen as a complementary energy contributor in the brain.
Melis Karaca, Francesca Frigerio, Stephanie Migrenne, Juliette Martin-Levilain, Dorte M. Skytt, Kamilla Pajecka, Rafael Martin-del-Rio, Rolf Gruetter, Jorge Tamarit-Rodriguez, Helle S. Waagepetersen, Christophe Magnan, Pierre Maechler   +11 more
doaj   +1 more source

Collaborative learning of images and geometrics for predicting isocitrate dehydrogenase status of glioma [PDF]

arXiv, 2022
The isocitrate dehydrogenase (IDH) gene mutation status is an important biomarker for glioma patients. The gold standard of IDH mutation detection requires tumour tissue obtained via invasive approaches and is usually expensive. Recent advancement in radiogenomics provides a non-invasive approach for predicting IDH mutation based on MRI.
arxiv  

Isoenzyme pattern of glutamate dehydrogenase as a reflection of nitrogen metabolism in Lupinus albus

Acta Societatis Botanicorum Poloniae, 2015
Glutamate dehydrogenase (L-glutamate: NAD dehydrogenase, EC 1.4. 1.2; GDH) activity and electrophoretic separation pattern of the enzyme were studied. The enzyme was extracted from embryos of Lupinus albus decotyledonized and cultured for 24, 48 and 72 ...
Lech Ratajczak, Wiktoria Ratajczak, Hanna Mazurowa   +2 more
doaj   +1 more source

Free Energy of Activation for the Comorosan Effect [PDF]

arXiv, 2007
Initial reaction rate data for lactic dehydrogenase / pyruvate, lactic dehydrogenase / lactate and malic dehydrogenase / malate enzyme reactions were analyzed to obtain activation free energy changes of -329, -195 and -221 cal/mole, respectively, for rate increases associated with time-specific irradiation of the crystalline substrates prior to ...
arxiv  

Carbon Paste Electrode Modified Poly-Glutamic Acid (PGA) with Molecularly Imprinted for Detection of Rhodamine B [PDF]

IOP Material Science and Engineering June 2021, 2020
Rhodamine B is a synthetic dye used for coloring textiles, paper and ceramics. In addition, Rhodamine B is also often used for coloring ingredients in food ingredients such as crackers, syrups, candy, cakes, and is often used for coloring lipsticks. The accumulation of Rhodamine B in the body can cause liver, kidney and lymph damage.
arxiv  

Glutamine-Glutamate Cycle Flux Is Similar in Cultured Astrocytes and Brain and Both Glutamate Production and Oxidation Are Mainly Catalyzed by Aspartate Aminotransferase

Biology, 2017
The glutamine-glutamate cycle provides neurons with astrocyte-generated glutamate/γ-aminobutyric acid (GABA) and oxidizes glutamate in astrocytes, and it returns released transmitter glutamate/GABA to neurons after astrocytic uptake.
Leif Hertz, Douglas L Rothman
doaj   +1 more source

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

Science's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

Evolution: The Case of the Glyceraldehyde-3-Phosphate Dehydrogenase Gene [PDF]

arXiv, 2000
The enzyme Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) catalyses the decomposition of glucose. The gene that produces the GAPDH is therefore present in a wide class of organisms. We show that for this gene the average value of the fluctuations in nucleotide distribution in the codons, normalized to strand bias, provides a reasonable measure of how
arxiv  

Molecular Characterization of the Iranian Isolates of Giardia Lamblia: Application of the Glutamate Dehydrogenase Gene [PDF]

Iranian Journal of Public Health, 2008
Background: This study was conducted to determine of molecular epidemiology of the Giardia lamblia by PCR-RFLP method in Tehran, capital of Iran. Methods: Thirty eight stool samples were randomly selected from 125 patients diagnosed with giardiasis using
L Akhlaghi, H Oormazdi, Z Babaei, S Rezaie, E Razmjou, SK Soltani- Arabshahi, AR Meamar, R Hadighi   +7 more
doaj   +2 more sources

Suppressive effect of Yokukansan on glutamate released from canine keratinocytes

Open Veterinary Journal
Background: Canine atopic dermatitis (CAD) is caused by skin barrier dysfunction due to allergen exposure. Excessive glutamate release in the skin is associated with delayed skin barrier function recovery and epidermal thickening and lichenification ...
Yoichiro Kasuga, Ailing Hu, Zenji Kawakami, Masahiro Tabuchi, Takuji Yamaguchi, Hiroyuki Kobayashi, Shigaku Ikeda   +6 more
doaj   +1 more source