Results 181 to 190 of about 2,596,775 (326)

Targeting Excitatory Glutamate Receptors for Morphine Tolerance: A Narrative Review. [PDF]

CNS Neurosci Ther
Huang M, Luo L, Wang W, Xu H, Chen M, Ma X, Xu T.   +6 more
europepmc   +1 more source

CB1 Receptor Activation Provides Neuroprotection in an Animal Model of Glutamate‐Induced Excitotoxicity Through a Reduction of NOX‐2 Activity and Oxidative Stress

Ataúlfo Martı́nez-Torres, Julio Morán   +1 more
openalex   +1 more source

Molecular mechanism of agonist recognition by the ligand‐binding core of the ionotropic glutamate receptor 4 [PDF]

, 2008
Christina Kasper, Karla Frydenvang, Peter Naur, Michael Gajhede, Darryl S. Pickering, J.S. Kastrup   +5 more
openalex   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Subarachnoid hemorrhage mediates human neocortical network, membrane potential, and action potential bursting via glutamate receptors. [PDF]

Commun Biol
Huang DF, Chou MY, Lee YH, Chen YT, Sun CK, Wang KC, Huang HS.   +6 more
europepmc   +1 more source

A Genome Wide Association Study Links Glutamate Receptor Pathway to Sporadic Creutzfeldt-Jakob Disease Risk

, 2015
Pascual Sánchez‐Juan, Matthew Bishop, Gábor G. Kovács, Miguel Calero, Yurii S. Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Ángel Carracedo, Sven J. van der Lee, Thomas Ströbel, Fernando Rivadeneira, Albert Hofman, Stéphane Haı̈k, Onofre Combarros, José Berciano, André G. Uitterlinden, Steven Collins, Herbert Budka, Jean‐Philippe Brandel, Jean Laplanche, Maurizio Pocchiari, Inga Zerr, Richard Knight, Robert Will, Cornelia M. van Duijn   +28 more
openalex   +2 more sources

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C-Neuroligin 3 Mouse Model of Autism Spectrum Disorder. [PDF]

J Neurochem
Meringolo M, Montanari M, D'Antoni S, Martella G, El Atiallah I, Ponterio G, Tassone A, Reverte I, Caprioli D, Strimpakos G, Pieroni L, Catania MV, Bonsi P.   +12 more
europepmc   +1 more source

Genomics and transcriptomic alterations of the glutamate receptors in acute myeloid leukemia. [PDF]

Clin Transl Sci, 2023
Alqahtani A, Wang M, Lou M, Alachkar H.
europepmc   +1 more source

Advancing the Tendinopathy Triad: Comment on “Tendinopathy: The Interplay Between Mechanical Stress, Inflammation, and Vascularity”

Advanced Science, EarlyView.
Abstract Building upon the integrative framework of tendinopathy proposed by Gehwolf et al.—which elegantly connects mechanical stress, inflammation, and vascularity—this commentary extends the discussion by introducing novel mechanistic insights and future research directions that move beyond the established triad. A paradigm shift is proposed ...
DuJiang Yang, Jiexiang Yang, Shuang Wang, GuoYou Wang   +3 more
wiley   +1 more source