Results 201 to 210 of about 8,454 (258)
Structural enzymology studies with the substrate 3S-hydroxybutanoyl-CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD. [PDF]
Sridhar S +4 more
europepmc +1 more source
A specific negatively charged sequence confers intramolecular regulation on Munc13-1 function in synaptic exocytosis. [PDF]
Zhao K +10 more
europepmc +1 more source
Structural and functional insights into extreme thermal stability and activity of two GH12 domains of a multidomain glycosidase from a hyperthermophilic euryarchaeon. [PDF]
Zayulina KS +11 more
europepmc +1 more source
RyR1-mediated Ca<sup>2+</sup>-induced Ca<sup>2+</sup> release plays a negligible role in excitation-contraction coupling of normal skeletal muscle. [PDF]
Kobayashi T +11 more
europepmc +1 more source
Structural basis of urea transport by Arabidopsis thaliana DUR3. [PDF]
An W +6 more
europepmc +1 more source
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Biological Psychiatry, 2013
Recent compelling evidence has suggested that the glutamate system is a primary mediator of psychiatric pathology and also a target for rapid-acting antidepressants. Clinical research in mood and anxiety disorders has shown alterations in levels, clearance, and metabolism of glutamate and consistent volumetric changes in brain areas where glutamate ...
L. Musazzi +3 more
openaire +2 more sources
Recent compelling evidence has suggested that the glutamate system is a primary mediator of psychiatric pathology and also a target for rapid-acting antidepressants. Clinical research in mood and anxiety disorders has shown alterations in levels, clearance, and metabolism of glutamate and consistent volumetric changes in brain areas where glutamate ...
L. Musazzi +3 more
openaire +2 more sources
European Neuropsychopharmacology, 2004
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink +2 more
openaire +2 more sources
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink +2 more
openaire +2 more sources
Neurochemical Research, 2015
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
openaire +2 more sources
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
openaire +2 more sources

