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Oxidative deamination of glutamate and transdeamination through glutamate

Archives of Biochemistry and Biophysics, 1966
Abstract Rat liver mitochondria are able to produce ammonia from glutamate at a steady rate under the conditions described. A system generating ADP from ATP is necessary for the continual deamination of glutamate. Maximum stimulation is reached with a hexokinase-glucose system in the presence of 0.2 m m ATP.
F J, Hird, M A, Marginson
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The Role of Glutamate Transporters in Glutamate Homeostasis in the Brain

Journal of Experimental Biology, 1997
ABSTRACT Glutamate transporters in neurones and glia, four of which have been cloned from mammals, play a crucial role in controlling the extracellular glutamate concentration in the brain. In normal conditions, they remove glutamate from the extracellular space and thereby help to terminate glutamatergic synaptic transmission and to ...
M, Takahashi   +5 more
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Glutamate uptake

Progress in Neurobiology, 2001
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
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Glutamate synthase and the synthesis of glutamate in plants

Plant Physiology and Biochemistry, 2003
The discovery of glutamate synthases (E.C. 1.4.1.13 and E.C. 1.4.7.1) caused a major re-assessment of the way in which ammonium is assimilated in bacteria and higher plants. The history of that discovery is reviewed and considered in the light of recent developments in the biochemistry and genetics of the higher plant ferredoxin- and NADH-dependent ...
Lea, Peter John, Miflin, Ben J.
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Glutamate receptors and new glutamate agonists

Trends in Pharmacological Sciences, 1983
Abstract A variety of naturally occurring and synthetic analogues of the putative excitatory amino acid neurotransmittersl-glutamic acid (l-GLU) andl-aspartec acid (l-ASP) are powerful neuroexcitatory and neurotoxic agents. These effects appear to be mediated primarily by the central receptors normally operated byl-GLU and/orl-ASP.
Povl Krogsgaard-Larsen, Tage Honore´
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Glutamate and Glutamate Receptors in the Vertebrate Retina

2023
Book chapter published in: Kolb, H., Fernandez, E., Nelson, R., Webvision: The Organization of the Retina and Visual System [Internet].
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Enzymatic production of d-glutamate from l-glutamate by a glutamate racemase

Journal of Fermentation and Bioengineering, 1995
Abstract d -Glutamate was produced from l -glutamate by two successive cellular reactions with a glutamate racemase produced by Escherichia coli TM93 harboring a plasmid containing a glutamate racemase gene from Lactobacillus brevis ATCC 8287 and a glutamate decarboxylase produced by E. coli ATCC 11246.
Makoto Yagasaki   +3 more
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Glutamate and Orexin Neurons

2012
Orexin neurons are localized in the lateral hypothalamus and regulate many functions including sleep-wake states. Substantial number of neurotransmitters and neuromodulators has been proposed to influence orexinergic system. Glutamate, as the major excitatory amino acid neurotransmitter in the hypothalamus, was shown to mediate orexin neurons in the ...
Minbay, Zehra   +2 more
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Glutamate

Headache Currents, 2004
The NMDA Receptor Antagonist MK‐801 Reduces Fos‐like Immunoreactivity Within the Trigeminocervical Complex Following Superior Sagittal Sinus Stimulation in the Cat Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following trigeminovascular nociceptive
Jonas Broman   +4 more
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Glutamate Receptors and Glutamate Corticofugal Pathways

1986
Although the neurochemical anatomy of many pathways in human brain has been studied, little attention has been paid to the human pyramidal system. This pathway is very important for voluntary motor control in vertebrates, and pyramidal tract pathology leads to hemiparesis or hemiplegia in primates and man (Phillips and Porter, 1977).
A. B. Young   +3 more
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