Results 331 to 340 of about 226,163 (382)

Glutamate receptors and new glutamate agonists

Trends in Pharmacological Sciences, 1983
Abstract A variety of naturally occurring and synthetic analogues of the putative excitatory amino acid neurotransmittersl-glutamic acid (l-GLU) andl-aspartec acid (l-ASP) are powerful neuroexcitatory and neurotoxic agents. These effects appear to be mediated primarily by the central receptors normally operated byl-GLU and/orl-ASP.
Tage Honore, Povl Krogsgaard-Larsen
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The Role of Glutamate Transporters in Glutamate Homeostasis in the Brain

Journal of Experimental Biology, 1997
ABSTRACT Glutamate transporters in neurones and glia, four of which have been cloned from mammals, play a crucial role in controlling the extracellular glutamate concentration in the brain. In normal conditions, they remove glutamate from the extracellular space and thereby help to terminate glutamatergic synaptic transmission and to ...
Brian Billups, David Attwell, David J. Rossi, Monique Sarantis, Martine Hamann, Michiko Takahashi   +5 more
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Oxidative deamination of glutamate and transdeamination through glutamate

Archives of Biochemistry and Biophysics, 1966
Abstract Rat liver mitochondria are able to produce ammonia from glutamate at a steady rate under the conditions described. A system generating ADP from ATP is necessary for the continual deamination of glutamate. Maximum stimulation is reached with a hexokinase-glucose system in the presence of 0.2 m m ATP.
F.J.R. Hird, M.A. Marginson
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Glutamate and Glutamate Receptors in the Vertebrate Retina

2023
Book chapter published in: Kolb, H., Fernandez, E., Nelson, R., Webvision: The Organization of the Retina and Visual System [Internet].
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Glutamate carboxypeptidase

2004
Publisher Summary This chapter describes the activity, specificity and structural chemistry of glutamate carboxypeptidase. Glutamate carboxypeptidases are characterized as Zn2+ requiring exopeptidases with specificity for glutamate and this specificity is not absolute as carboxypeptidase G was reported as exhibiting activity against pteroyl compounds ...
Roger F. Sherwood (Deceased), Roger G. Melton   +1 more
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Localization of glutamate and glutamate transporters in the sensory neurons ofAplysia [PDF]

The Journal of Comparative Neurology, 2000
The sensorimotor synapse of Aplysia has been used extensively to study the cellular and molecular basis for learning and memory. Recent physiologic studies suggest that glutamate may be the excitatory neurotransmitter used by the sensory neurons (Dale and Kandel [1993] Proc Natl Acad Sci USA. 90:7163-7167; Armitage and Siegelbaum [1998] J Neurosci.
Jeannie Chin, Laurence Dryer, John H. Byrne, Jonathan M. Levenson, David M. Sherry, Arnold Eskin   +5 more
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Enzymatic production of d-glutamate from l-glutamate by a glutamate racemase

Journal of Fermentation and Bioengineering, 1995
Abstract d -Glutamate was produced from l -glutamate by two successive cellular reactions with a glutamate racemase produced by Escherichia coli TM93 harboring a plasmid containing a glutamate racemase gene from Lactobacillus brevis ATCC 8287 and a glutamate decarboxylase produced by E. coli ATCC 11246.
Masaki Azuma, Akio Ozaki, Shuichi Ishino, Makoto Yagasaki   +3 more
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Glutamate Receptors and Glutamate Corticofugal Pathways

1986
Although the neurochemical anatomy of many pathways in human brain has been studied, little attention has been paid to the human pyramidal system. This pathway is very important for voluntary motor control in vertebrates, and pyramidal tract pathology leads to hemiparesis or hemiplegia in primates and man (Phillips and Porter, 1977).
Anne B. Young, Mark B. Bromberg, J. B. Penney, J. T. Greenamyre   +3 more
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Role of Glutamate Receptors and Glutamate Transporters in the Regulation of the Glutamate-Glutamine Cycle in the Awake Rat

Neurochemical Research, 1999
In the present study we investigate the effects of a specific glutamate reuptake blocker, L-trans-pyrrolidine-3,4-dicarboxylic acid (PDC), on extracellular concentrations of glutamine and glutamate in the striatum of the freely moving rat. Intracerebral infusions of PDC (1, 2 and 4 mM) produced a dose-related increase in extracellular concentrations of
Francisco Mora, Gregorio Segovia, Alberto Del Arco   +2 more
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Genotoxicity of monosodium glutamate

Food and Chemical Toxicology, 2016
Monosodium glutamate (MSG) is one of the most widely used flavor enhancers throughout the world. The aim of this study is to investigate the genotoxic potential of MSG by using chromosome aberrations (CAs), sister-chromatid exchanges (SCEs), cytokinesis-blocked micronucleus (CBMN), and random amplified polymorphic DNA-polimerase chain reaction (RAPD ...
Ataseven, Nazmiye, Yuzbasioglu, Deniz, Keskin, Ayten Celebi, Unal, Fatma   +3 more
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