Results 111 to 120 of about 5,211,997 (349)

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu   +9 more
wiley   +1 more source

Solvent‐Rich Pre‐Coagulation Bath for Tunable Liquid‐State Fusion Enables Robust Two‐Step Polymer Embedded Printing

open access: yesAdvanced Science, EarlyView.
Additive manufacturing enables complex structures, but polymer printing often suffers from poor interlayer fusion and defects induced by heat or binders. A two‐step, room‐temperature strategy based on immersion phase separation (IPS‐E3DP) achieves precise liquid‐state fusion with high structural fidelity, enhanced mechanical performance, broad material
Kaidong Song   +11 more
wiley   +1 more source

Hsa_circ_0026782 Acts as a “Molecular Break” of CREB1‐Mediated Transcription by Promoting Its Phosphorylation at Ser142 That Prevents Keloid Progression

open access: yesAdvanced Science, EarlyView.
Model for the role of hsa_circ_0026782/p‐CREB1 (Ser142) played in keloid. Hsa_circ_0026782 is derived from back‐splicing of ITGA7 exon 4. When hsa_circ_0026782 binds to CREB1, the exposure of the bZIP domain and dimerization of CREB1 are promoted (upper left).
Xin‐Cao Zhong   +10 more
wiley   +1 more source

Luminescent Nanocucurbits Enable Spatiotemporal Co‐Delivery of Hydrophilic and Hydrophobic Chemotherapeutic Agents

open access: yesAdvanced Science, EarlyView.
A cucurbit‐shaped luminescent nanoparticle (nanocucurbit) is engineered through the self‐assembly of polypeptides conjugated with aggregation‐induced emission (AIE) fluorophore. The resulting nanocucurbit exhibits approximately two‐fold higher cellular internalization efficiency compared to its spherical counterparts.
Ping Wei   +4 more
wiley   +1 more source

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

open access: yesAdvanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie   +8 more
wiley   +1 more source

“FOLIC ACID” ACTIVITY OF N-(4-(4-QUINAZOLINE)BENZOYL)GLUTAMIC ACID

open access: hybrid, 1947
Gustav J. Martin   +2 more
openalex   +1 more source

One‐Pot Encapsulation of Enzymes in a Calcium Carboxylate Metal‐Organic Framework for Improved Buffer Stability

open access: yesAdvanced Science, EarlyView.
A biocompatible, room‐temperature synthesis of Ca2⁺–4,5‐imidazoledicarboxylate MOFs enables in situ encapsulation of diverse enzymes with enhanced stability in phosphate buffer. A machine learning workflow integrating Latin hypercube sampling efficiently navigates the synthesis space, optimizing encapsulation efficiency, retained enzymatic activity ...
Ying Shu, Weibin Liang, Jun Huang
wiley   +1 more source

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