Results 151 to 160 of about 278,769 (333)

THE SIGNIFICANCE OF GLUTAMIC DEHYDROGENASE IN GLUTAMIC ACID FERMENTATION

open access: yesThe Journal of General and Applied Microbiology, 1962
1. The activity to synthesize aspartic acid from fumaric acid and ammonia and the activity to synthesize glutamic acid from citric acid and ammonia were examined with the cell-free extracts obtained from several strains of M. glutamicus and their mutants grown on glucose bouillon media.
openaire   +3 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

The metabolomics of psoriatic disease. [PDF]

open access: yes, 2017
Metabolomics is an emerging new "omics" field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes ...
Afifi, Ladan   +6 more
core  

Recombinant Expression and Bioprocess Optimization of Priestia megaterium α‐Amylase and Its Impact on Dough Fermentation Efficiency

open access: yesChemistry &Biodiversity, EarlyView.
This study presents a scalable strategy for producing Priestia megaterium α‐amylase (PmAmy) via fed‐batch fermentation, optimizing the biomass/IPTG ratio to enhance yield. With an activity of 67.7 U mL−1 at 22.3 g L−1 biomass, PmAmy demonstrated 99% efficiency in dough fermentation, highlighting its industrial potential as a sustainable baking enzyme .
Atacan Erdem   +3 more
wiley   +1 more source

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

open access: yesChemBioChem, EarlyView.
Previous studies reveal an unexpected tendency for amyloid aggregation in specific regions of the C‐terminal domain (CTD) of nucleophosmin 1 (NPM1), a nucleolar chaperone involved in acute myeloid leukemia (AML). Herein, several peptide analogs of NPM1264‐277 (amyloid core) with conservative substitutions are designed and evaluated through biophysical ...
Daniele Florio   +7 more
wiley   +1 more source

A De Novo Designed Metalloprotein Displays Variable Thermal Stability and Binding Stoichiometry with Transition Metal Ions

open access: yesChemBioChem, EarlyView.
A de novo designed single‐chain coiled coil protein is unfolded in apo‐state but folds up upon addition of divalent transition metal ions Co(II), Ni(II), Cu(II), and Zn(II). The resulting metal‐bound complexes exhibit distinct thermal stability and metal stoichiometry, making this protein a promising starting point for the design of fully metal ...
Britt Rooijakkers   +4 more
wiley   +1 more source

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