Reversible Sterilization of Channel Catfish via Overexpression of Glutamic Acid Decarboxylase Gene. [PDF]
Ye Z+14 more
europepmc +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
In Silico Evaluation of Some Computer-Designed Fluoroquinolone-Glutamic Acid Hybrids as Potential Topoisomerase II Inhibitors with Anti-Cancer Effect. [PDF]
Oancea OL+4 more
europepmc +1 more source
Research progress of neurovascular units involved in ischemic stroke
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang+4 more
wiley +1 more source
Differences in the Renal Accumulation of Radiogallium-Labeled (Glu)14 Peptides Containing Different Optical Isomers of Glutamic Acid. [PDF]
Ogawa K+7 more
europepmc +1 more source
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen+10 more
wiley +1 more source
Electrofermentation increases concentration of poly γ-glutamic acid in Bacillus subtilis biofilms. [PDF]
Adilkhanova A+9 more
europepmc +1 more source
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan+7 more
wiley +1 more source
Impact of aspect ratio and crystal size distribution of l-glutamic acid formed by cooling crystallization on drying characteristics. [PDF]
Lee JB+9 more
europepmc +1 more source
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
wiley +1 more source