Results 261 to 270 of about 294,800 (348)

A new microassay method for L-glutamic acid decarboxylase (GAD) activity

, 1974
Hiroshi Kimurâ, Klnya Kuriyama
openalex   +1 more source

Tuning adsorption and morphology in poly(glutamic acid) via controlled acidic partial deprotection

Polymer International, EarlyView.
Partial deprotection of poly(glutamic acid) generates morphologies and assemblies that match fully deprotected polypeptides in small‐molecule adsorption, extending to block copolypeptides with pH‐dependent effects. Abstract Synthetic polypeptides prepared from N‐carboxyanhydride (NCA) monomers are important platforms for environmental and medical ...
Hunter Wood, Stella Trickett, Joseph Dosch, Farin Weinger, Dan Flaherty, Stefanie Sydlik   +5 more
wiley   +1 more source

Poly-γ-glutamic acid alleviates slow transit constipation by regulating aquaporin and gut microbes. [PDF]

Sci Rep
Wang X, Zhou J, Sun Z, Jia R, Huang D, Tang D, Xia T, Xiao F.   +7 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Improvement of semen quality in Longyou Partridge Chicken by dietary N-acetyl-L-glutamic acid and its mechanism study. [PDF]

Poult Sci
Du X, Tong X, Qian X, Zhang Y, Li D, Liu X, Zheng X, Zhao A.   +7 more
europepmc   +1 more source

Controlling the Assembly of Ureido‐Pyrimidinone Supramolecular Monomers by Tuning the Hydrophilic‐Hydrophobic Balance

Journal of Polymer Science, EarlyView.
In this study, the self‐assembly behavior of water‐compatible UPy‐based supramolecular monomers with varying hydrophilic‐hydrophobic balances is systematically investigated. Experimental and computational analyses reveal that the molecular monomer design is pivotal in steering the self‐assembly properties, highlighting the role of alkyl‐urea spacers in
Riccardo Bellan, Annalisa Cardellini, Claudio Perego, Lars J. M. M. Paffen, Laura Rijns, Giovanni M. Pavan, Patricia Y. W. Dankers   +6 more
wiley   +1 more source

Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen-Specific Tolerance Without Alloreactivity. [PDF]

Arthritis Rheumatol
Jha V, Freed BM, Sunderhaus ER, Lee JE, Prage EB, Miglani M, Rosloniec EF, Matsuda JL, Coulombe MG, McKee AS, Roark CL.   +10 more
europepmc   +1 more source

Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47–55

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys, Marco Giulini, Vlad Cojocaru, Anna Engel, Xiaotong Xu, Jorge Roel‐Touris, Cunliang Geng, Francesco Ambrosetti, Brian Jiménez‐García, Zuzana Jandova, Panagiotis I. Koukos, Charlotte van Noort, João M. C. Teixeira, Siri C. van Keulen, Manon Réau, Rodrigo V. Honorato, Alexandre M. J. J. Bonvin   +16 more
wiley   +1 more source

Clinical Features of Glutamic Acid Decarboxylase-65 Neurological Autoimmunity: A Case Series From China. [PDF]

CNS Neurosci Ther
Qiu Z, Xu F, Zhang M, Yang X, Han Y, Li D, Liu L, Chen J, Gao L, Xue Q, Hou Y, Sun Y, Di L, Fan C, Liang J, Han Y, Dong H, Hao J, Liu Z.   +18 more
europepmc   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source