Results 91 to 100 of about 838,663 (376)

Evaluation of HSP70 deficiency in the inflammatory response in vivo and in vitro: The impact of HSP90 expression, glucocorticoid release, and glutamine administration

Journal of Biological Research - Thessaloniki, 2022
The present study aimed to explore the pathway through which Heat Shock Protein 70 (HSP70) is involved in inflammation and sepsis and the possible interaction with glutamine, an essential nutrient during sepsis. We also evaluated the possible interaction
Ioanna Plati, Olga Rassouli, Eirini Dermitzaki, Eleftheria Ieronymaki, George Briassoulis, Maria Venihaki   +5 more
doaj   +1 more source

Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue [PDF]

, 1912
Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue. Decreased ammonium (NH4+) excretion is associated with hyperkalemia.
Raymond S. Sleeper, Pierre Belanger, Guy Lemieux, Harry G. Preuss, Szylman, Hulter, Tannen, Kamm, Schwartz, Iacobellis, Iacobellis, Tannen, Tannen, Cartier, Preuss, Weiss, Preuss, Williamson, Oye, Meiss, Pilkington, Roxe, Preuss, Preuss, Preuss, Preuss, Leutscher, Conn, Milne, Schloeder, Sapir, Pagliara, Kamm, Sleeper, Chester, Sastrasinh, Vinay, Pitts, Lemieux, Lamar, Krebs, Braunstein, Bendal, Quagliariello, Preuss, Pitts, Kovacevic, Crompton, Relman, Lemieux, Bogusky, Tannen, Preuss, Preuss, Black, Clarke, Anderson, Bavarel, Cross, Preuss, Reimer   +60 more
core   +1 more source

Effects of glutamine and n-3 polyunsaturated fatty acid mixed lipid emulsion supplementation of parenteral nutrition on sepsis score and bacterial clearance in early experimental sepsis [PDF]

, 2023
Qing Ma, Paul E. Wischmeyer
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Glutamine supplementation to prevent morbidity and mortality in preterm infants [PDF]

, 2016
BACKGROUND: Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Evidence exists that glutamine supplementation improves clinical outcomes in critically ill adults.
Brown, Jennifer Ve, McGuire, William, Moe-Byrne, Thirimon   +2 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Production of Corn Protein Hydrolysate with Glutamine-Rich Peptides and Its Antagonistic Function in Ulcerative Colitis In Vivo

Foods, 2022
Ulcerative colitis is a typical chronic inflammatory disease of the gastrointestinal tract, which has become a serious hazard to human health. The purpose of the present study was to evaluate the antagonistic effect of corn protein hydrolysate with ...
Yan Jing, Xiaolan Liu, Jinyu Wang, Yongqiang Ma, Xiqun Zheng   +4 more
doaj   +1 more source

Parenteral glutamine in critical illness : just what the gut needs [PDF]

, 2012
The role of glutamine as a metabolic fuel for the starving intestines, its capacity to limit bacterial translocation, lung sepsis and a pro-inflammatory cytokine response are reviewed in the context of uncertainities regarding current recommendations for
Pullicino, Edgar
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Gene expression profiling indicates a shift in ammonia assimilation capacity along the hepatic acinus induced by different forms of selenium in vitamin–mineral mixes fed to beef steers grazing on toxic endophyte-infected tall fescue

Frontiers in Animal Science, 2023
Recently, we demonstrated that supplementing (with 3 mg Se per day) the diets of growing beef steers grazing on Se-deficient toxic endophyte-infected tall fescue-based forage with either organic Se (OSe, SEL-PLEX) or a 1:1 blend (MIX) of OSe and ...
Yang Jia, Kwangwon Son, James C. Matthews   +2 more
doaj   +1 more source