Results 341 to 350 of about 838,663 (376)

‌PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation. [PDF]

Sci Rep
Gan Y, Wei W, Jiang B, Zhang X, Jiang L, Teng L, Xie X, Liu Y, Xie Q, Jiang L.   +9 more
europepmc   +1 more source

Comprehensive bioinformatics analysis identified and validated KIT as a key gene associated with glutamine metabolism in thyroid carcinoma. [PDF]

Medicine (Baltimore)
Li X, Qiu L, Gu E, Ke N, Fang M.
europepmc   +1 more source

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Glutamine

2012
Glutamine (GLN) has been shown to be a key pharmaconutrient in the body's response to stress and injury. It exerts its protective effects via multiple mechanisms, including direct protection of cells and tissue from injury, attenuation inflammation, and preservation of metabolic function.
Mike, Kim, Paul E, Wischmeyer
  +7 more sources

Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria

Science Translational Medicine, 2021
Description Multidrug-resistant Escherichia coli metabolomes are reprogrammed by glutamine to be sensitive to ampicillin in vitro and in vivo. A metabolite to mitigate antimicrobial resistance Antibiotic resistance is a pervasive and increasing problem ...
Xiangyang Zhao, Zhuang-gui Chen, Tia Yang, Ming Jiang, Jie Wang, Zhi-xue Cheng, Man-jun Yang, Jia-xin Zhu, Tian-tuo Zhang, Hui Li, Bo Peng, Xuan-xian Peng   +11 more
semanticscholar   +1 more source

Glutamine

World Journal of Surgery, 2000
AbstractRelatively little was known about glutamine metabolism until the 1930s, when Sir Hans Krebs first demonstrated glutamine hydrolysis and biosynthesis in the kidney. Subsequent studies by Rose in 1938 demonstrated that glutamine is a nonessential (dispensable) amino acid, as it can be readily synthesized de novo in virtually all tissues in the ...
B I, Labow, W W, Souba
openaire   +2 more sources

Congenital Glutamine Deficiency with Glutamine Synthetase Mutations

New England Journal of Medicine, 2005
Glutamine synthetase plays a major role in ammonia detoxification, interorgan nitrogen flux, acid-base homeostasis, and cell signaling. We report on two unrelated newborns who had congenital human glutamine synthetase deficiency with severe brain malformations resulting in multiorgan failure and neonatal death.
Johannes, Häberle, Boris, Görg, Frank, Rutsch, Eva, Schmidt, Annick, Toutain, Jean-François, Benoist, Antoinette, Gelot, Annie-Laure, Suc, Wolfgang, Höhne, Freimut, Schliess, Dieter, Häussinger, Hans G, Koch   +11 more
openaire   +2 more sources

Origin and Roles of Alanine and Glutamine in Gluconeogenesis in the Liver, Kidneys, and Small Intestine under Physiological and Pathological Conditions

International Journal of Molecular Sciences
Alanine and glutamine are the principal glucogenic amino acids. Most originate from muscles, where branched-chain amino acids (valine, leucine, and isoleucine) are nitrogen donors and, under exceptional circumstances, a source of carbons for glutamate ...
M. Holeček
semanticscholar   +1 more source

Plasma glutamine response to enteral administration of glutamine in human volunteers (free glutamine versus protein-bound glutamine)

Nutrition, 2000
The goal of the present work was to compare the plasma glutamine response to exogenous glutamine administration in human volunteers; glutamine was provided as a free amino acid, bound to proteins, or in the form of peptides. Plasma glutamine concentrations were measured in eight human volunteers at 30, 60, 90, 120, and 240 min after receiving a drink ...
J J, Boza, J, Maire, L, Bovetto, O, Ballèvre   +3 more
openaire   +2 more sources