Results 211 to 220 of about 178,237 (260)
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Journal of Parenteral and Enteral Nutrition, 1990
A fundamental conceptional change in the field of hepatic glutamine metabolism is derived from an understanding of the unique regulatory properties of hepatic glutaminase, the occurrence of glutamine cycling, and the discovery of marked hepatocyte heterogeneities in nitrogen metabolism, with metabolic interactions between differently localized ...
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A fundamental conceptional change in the field of hepatic glutamine metabolism is derived from an understanding of the unique regulatory properties of hepatic glutaminase, the occurrence of glutamine cycling, and the discovery of marked hepatocyte heterogeneities in nitrogen metabolism, with metabolic interactions between differently localized ...
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Glutamine Metabolism in Gliomas
2016By histological, morphological criteria, and malignancy, brain tumors are classified by WHO into grades I (most benign) to IV (highly malignant), and gliomas are the most frequently occurring class throughout the grades. Similar to peripheral tumors, the growth of glia-derived tumor cells largely depends on glutamine (Gln), which is vividly taken up by
Monika, Szeliga, Jan, Albrecht
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Glutamine Metabolism in Cancer
2018Metabolism is the fundamental process for all cellular functions. For decades, there has been growing evidence with regard to the relationship between metabolism and malignant cell proliferation. Unlike normal differentiated cells, however, cancer cells have reprogrammed metabolisms in order to fulfill their energy requirements.
Ting, Li, Anne, Le
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Metabolism of glutamine in lymphocytes
Metabolism, 1989Pathways of glutamine metabolism in resting and proliferating rat thymocytes and established human T- and B-lymphoblastoid cell lines were evaluated by in vitro incubations of freshly prepared or cultured cells for one to two hours with [U14C]glutamine.
K, Brand +5 more
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Endotoxin and Renal Glutamine Metabolism
Archives of Surgery, 1991The effect of endotoxin on renal glutamine metabolism and ammoniagenesis was investigated in vivo in the rat to gain further insight into the altered glutamine flow that characterizes critical illness. Studies were done 15 hours following a single dose of Escherichia coli lipopolysaccharide (10 mg/kg).
T R, Austgen +3 more
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Glutamine metabolism in human lymphocytes
Clinical Nutrition, 1990The data indicate that glutamine plays a critical role in the metabolism of human lymphocytes stimulated in vitro and in vivo. The understanding of these processes is a prerequisite if one is to substitute glutamine under conditions of compromised lymphocyte function.
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Glutamine: A New Metabolic Substrate
1982Glutamine serves important metabolic functions in a variety of tissues, but it has only recently been recognized as a new component of the metabolism of bone-Glutamine and glutamate are present as free amino acids in bone water at concentrations 2.5 and 40 times greater than their respective concentrations in plasma. The mediated transport of glutamine
R M, Biltz +3 more
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Metabolic acidosis stimulates intestinal glutamine absorption
Gastroenterology, 2003Glutamine is an essential nutrient for cell integrity during acidotic states such as shock, but the effect of extracellular pH on intestinal mucosal cell glutamine uptake is poorly understood. The purpose of this in vitro study was to investigate the intracellular signaling pathways involved in controlling intestinal glutamine transport during acidosis.
Mark J, Epler +6 more
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Glutamine and Alanine Metabolism in NIDDM
Diabetes, 1996Gluconeogenesis is increased in NIDDM. We therefore examined the metabolism of glutamine and alanine, the most important gluconeogenic amino acids, in 14 postabsorptive NIDDM subjects and 18 nondiabetic volunteers using a combination of isotopic ([6-3H] glucose (20 µCi, 0.2 µCi/min), [U-14C]glutamine (20 µCi, 0.2 µCi/min), [3-13C]alanine (99% 13C, 2 ...
Michael Stumvoll +10 more
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Response of glutamine metabolism to exogenous glutamine in humans
American Journal of Physiology-Endocrinology and Metabolism, 1995To determine whether exogenous glutamine affects whole body glutamine metabolism, preliminary experiments were performed to verify that L-[1-13C]-, L-[U-14C]-, and L-[3,4-3H]glutamine given simultaneously by vein provided similar estimates of glutamine appearance rates [Ra; 355 +/- 24, 373 +/- 19, and 393 +/- 24 (SE) mumol.kg-1.h-1, respectively, P ...
R G, Hankard +5 more
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