Results 221 to 230 of about 183,364 (258)
Some of the next articles are maybe not open access.
Journal of Parenteral and Enteral Nutrition, 1990
The role of the lungs in maintaining amino acid homeostasis has only recently been studied. The data suggest that the lungs play a key role in glutamine flow in both normal and catabolic states. Further studies are necessary to clarify the regulation of lung glutamine at the whole organ and cellular level.
W W, Souba, K, Herskowitz, D A, Plumley
openaire +2 more sources
The role of the lungs in maintaining amino acid homeostasis has only recently been studied. The data suggest that the lungs play a key role in glutamine flow in both normal and catabolic states. Further studies are necessary to clarify the regulation of lung glutamine at the whole organ and cellular level.
W W, Souba, K, Herskowitz, D A, Plumley
openaire +2 more sources
Journal of Parenteral and Enteral Nutrition, 1990
The gut plays a key role in interorgan glutamine metabolism in normal and catabolic states. During critical illness, the gut responds to prevailing metabolic pressures that may result in a temporary "reset" in interorgan glutamine flow. As the body recovers from the disease process, the alterations in gut glutamine metabolism revert to normal, which ...
W W, Souba +4 more
openaire +2 more sources
The gut plays a key role in interorgan glutamine metabolism in normal and catabolic states. During critical illness, the gut responds to prevailing metabolic pressures that may result in a temporary "reset" in interorgan glutamine flow. As the body recovers from the disease process, the alterations in gut glutamine metabolism revert to normal, which ...
W W, Souba +4 more
openaire +2 more sources
Metabolism of glutamine in lymphocytes
Metabolism, 1989Pathways of glutamine metabolism in resting and proliferating rat thymocytes and established human T- and B-lymphoblastoid cell lines were evaluated by in vitro incubations of freshly prepared or cultured cells for one to two hours with [U14C]glutamine.
K, Brand +5 more
openaire +2 more sources
Nutrition, 2002
Expression of high activities of both glutamine synthetase and glutaminase allows the liver to play a major role in the regulation of glutamine homeostasis. The liver shows net glutamine output in metabolic acidosis, in prolonged starvation and animals bearing tumors, net glutamine uptake in the postabsorptive state, on consuming high protein diets ...
Malcolm, Watford +4 more
openaire +3 more sources
Expression of high activities of both glutamine synthetase and glutaminase allows the liver to play a major role in the regulation of glutamine homeostasis. The liver shows net glutamine output in metabolic acidosis, in prolonged starvation and animals bearing tumors, net glutamine uptake in the postabsorptive state, on consuming high protein diets ...
Malcolm, Watford +4 more
openaire +3 more sources
Glutamine Metabolism in Cancer
2018Metabolism is the fundamental process for all cellular functions. For decades, there has been growing evidence with regard to the relationship between metabolism and malignant cell proliferation. Unlike normal differentiated cells, however, cancer cells have reprogrammed metabolisms in order to fulfill their energy requirements.
Ting, Li, Anne, Le
openaire +2 more sources
Glutamine and Alanine Metabolism in NIDDM
Diabetes, 1996Gluconeogenesis is increased in NIDDM. We therefore examined the metabolism of glutamine and alanine, the most important gluconeogenic amino acids, in 14 postabsorptive NIDDM subjects and 18 nondiabetic volunteers using a combination of isotopic ([6-3H] glucose (20 µCi, 0.2 µCi/min), [U-14C]glutamine (20 µCi, 0.2 µCi/min), [3-13C]alanine (99% 13C, 2 ...
Michael Stumvoll +10 more
openaire +2 more sources
Targeting the glutamine-arginine-proline metabolism axis in cancer
Journal of Enzyme Inhibition and Medicinal ChemistryMetabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism.
Jiang-Jie Duan +2 more
exaly +3 more sources
Glutamine Metabolism in Gliomas
2016By histological, morphological criteria, and malignancy, brain tumors are classified by WHO into grades I (most benign) to IV (highly malignant), and gliomas are the most frequently occurring class throughout the grades. Similar to peripheral tumors, the growth of glia-derived tumor cells largely depends on glutamine (Gln), which is vividly taken up by
Monika, Szeliga, Jan, Albrecht
openaire +2 more sources
Response of glutamine metabolism to exogenous glutamine in humans
American Journal of Physiology-Endocrinology and Metabolism, 1995To determine whether exogenous glutamine affects whole body glutamine metabolism, preliminary experiments were performed to verify that L-[1-13C]-, L-[U-14C]-, and L-[3,4-3H]glutamine given simultaneously by vein provided similar estimates of glutamine appearance rates [Ra; 355 +/- 24, 373 +/- 19, and 393 +/- 24 (SE) mumol.kg-1.h-1, respectively, P ...
R G, Hankard +5 more
openaire +2 more sources
Journal of Parenteral and Enteral Nutrition, 1990
A fundamental conceptional change in the field of hepatic glutamine metabolism is derived from an understanding of the unique regulatory properties of hepatic glutaminase, the occurrence of glutamine cycling, and the discovery of marked hepatocyte heterogeneities in nitrogen metabolism, with metabolic interactions between differently localized ...
openaire +2 more sources
A fundamental conceptional change in the field of hepatic glutamine metabolism is derived from an understanding of the unique regulatory properties of hepatic glutaminase, the occurrence of glutamine cycling, and the discovery of marked hepatocyte heterogeneities in nitrogen metabolism, with metabolic interactions between differently localized ...
openaire +2 more sources