Results 151 to 160 of about 78,410 (212)

Targeting glutamine synthetase with AS1411-modified exosome-liposome hybrid nanoparticles for inhibition of choroidal neovascularization. [PDF]

J Nanobiotechnology
Zhang M, Lu X, Luo L, Dou J, Zhang J, Li G, Zhao L, Sun F.   +7 more
europepmc   +1 more source

Development and marker-trait relationships of functional markers for glutamine synthetase GS1 and GS2 homoeogenes in bread wheat. [PDF]

Mol Breed, 2023
Pascual L, Solé-Medina A, Faci I, Giraldo P, Ruiz M, Benavente E.   +5 more
europepmc   +1 more source

Transfer RNA and small molecule therapeutics for aminoacyl‐tRNA synthetase diseases

The FEBS Journal, Volume 292, Issue 11, Page 2737-2750, June 2025.
Aminoacyl‐tRNA synthetases catalyze the ligation of a specific amino acid to a cognate tRNA—a reaction that lays the foundations for deciphering the genetic code. Pathogenic alleles in these synthetases can lead to dominant or recessive disorders, for which little or no disease‐specific treatments exist.
Tristan N. Samuels, Fanqi Wu, Maria Mahmood, Wajd A. Abuzaid, Nancy Sun, Angelica Moresco, Victoria M. Siu, Patrick O'Donoghue, Ilka U. Heinemann   +8 more
wiley   +1 more source

Antisense RNA regulates glutamine synthetase in a heterocyst-forming cyanobacterium. [PDF]

Plant Physiol
Álvarez-Escribano I, Suárez-Murillo B, Brenes-Álvarez M, Vioque A, Muro-Pastor AM.   +4 more
europepmc   +1 more source

Glutamine synthetase gene PpGS1.1 negatively regulates the powdery mildew resistance in Kentucky bluegrass. [PDF]

Hortic Res, 2022
Sun X, Xie F, Chen Y, Guo Z, Dong L, Qin L, Shi Z, Xiong L, Yuan R, Deng W, Jiang Y.   +10 more
europepmc   +1 more source

Neural Metabolic Networks: Key Elements of Healthy Brain Function

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
This review originated from the Fourth International Society for Neurochemistry (ISN) and Journal of Neurochemistry (JNC) Flagship School (2022). Here, we describe how the specific bioenergetic profiles and metabolic exchanges between brain cells enable and gate synaptic function and behavior. Then, based on this analysis, we discuss the potential role
Nimrod Madrer, Nirma D. Perera, Nonthué A. Uccelli, Alice Abbondanza, Jens V. Andersen, Emma Veronica Carsana, Matthew D. Demmings, Regina F. Fernandez, Matheus Garcia de Fragas, Ismail Gbadamosi, Divita Kulshrestha, Ricardo A. S. Lima‐Filho, Oana C. Marian, Kia H. Markussen, Andrew J. McGovern, Elliott S. Neal, Sukanya Sarkar, Eva Šimončičová, Jazmín Soto‐Verdugo, Sozerko Yandiev, Ignacio Fernández‐Moncada   +20 more
wiley   +1 more source

Dynamics of glutamine synthetase expression in hepatic ischemia-reperfusion injury: Implications for therapeutic interventions. [PDF]

World J Hepatol
Huang ZH, Dong MQ, Liu FY, Zhou WJ.
europepmc   +1 more source

Glutamine synthetase (GS) knockout (KO) using CRISPR/Cpf1 diversely enhances selection efficiency of CHO cells expressing therapeutic antibodies. [PDF]

Sci Rep, 2023
Srila W, Baumann M, Riedl M, Rangnoi K, Borth N, Yamabhai M.   +5 more
europepmc   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, Volume 297, Issue 6, Page 584-607, June 2025.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

Phytosulfokine peptide optimizes plant growth and defense via glutamine synthetase GS2 phosphorylation in tomato. [PDF]

EMBO J, 2023
Ding S, Lv J, Hu Z, Wang J, Wang P, Yu J, Foyer CH, Shi K.   +7 more
europepmc   +1 more source